Results 81 to 90 of about 749,005 (154)
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.ABSTRACT Opioid receptor antagonists increase the plasma membrane density of μ‐opioid receptors (MOR) in vivo, thereby inducing “supersensitivity” to opioid agonists. This phenomenon increases the risk of overdose in patients that were being treated with naltrexone (Ntx), a popular MOR antagonist.
Stephen N. Grant +2 more
wiley +1 more source
Beta-arrestins operate an on/off control switch for focal adhesion kinase activity. [PDF]
Cell Mol Life Sci, 2020 Alexander RA +13 more
europepmc +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.ABSTRACT Incretin effect helps in regulating glucose homeostasis and maintaining glycaemic control within the human body. This effect is achieved by the two naturally occurring incretin hormones: glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1).
Nora H. J. Alharbi
wiley +1 more source
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz +8 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 20, Page 6007-6027, October 2026.Background and Purpose G protein‐coupled receptors (GPCRs) are integral membrane proteins that mediate physiological processes by enabling cells to detect and respond to diverse stimuli. Although many subfamily‐specific functional hotspots have been described, the family‐wide determinants of common and subfamily‐specific functions remain incomplete ...
Berkay Selçuk +3 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon +3 more
wiley +1 more source
IC 087 Guide to Beta Beta Houston Records, 1969-2011 [PDF]
, 2019 The Beta Beta Houston records contains correspondence, ephemera, photos, scrapbooks and some realia that document the history of the Beta Beta Houston Chapter #648 at Texas Women\u27s University (TWU), Region 6 of Sigma Theta Tau International Honor ...
Beta Beta Houston
core +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.Abstract Clinically non‐functioning pituitary neuroendocrine tumors (NF‐PitNETs) lack effective medical therapies, and the role of somatostatin receptor ligands (SRLs) and dopamine agonists (DAs) in this setting is controversial. We evaluated the in vitro response of NF‐PitNETs to multiple SRL and/or DA treatments, focusing on the role of receptor ...
Claudia Campana +9 more
wiley +1 more source
, 1905 Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1905-1928.
Phi Beta Kappa +1 more
core
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Annexin A4 (A4) inhibits adenylyl cyclase 5 and may protect the heart during chronic β‐adrenergic stress. After 7 days of isoprenaline, A4‐deficient mice showed greater cardiomyocyte hypertrophy, prolonged action potentials, reduced Ito, preserved ICaL with altered activation, increased NCX1, and enhanced acute cAMP responsiveness compared with wild ...
Florentina Pluteanu +4 more
wiley +1 more source