Results 171 to 180 of about 913,637 (282)

Scale‐dependent assembly shapes taxon‐dependent responses of soil microbes to island isolation and area

Ecography, EarlyView.
The theory of island biogeography (TIB) remains contentious for microbes, as their immense dispersal potential and microscopic size may decouple diversity from classic isolation/area effects. We explicitly tested TIB scaling rules for soil bacteria and fungi across 20 oceanic islands using a rigorous multi‐scale framework that integrated high ...
Lan Liu, Zuzana Münzbergová, Lele Jiang, Long Chen, Shurong Zhou   +4 more
wiley   +1 more source

Phenotyping patients with chronic obstructive pulmonary disease and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 900-911, April 2025.
Central illustration. Abbreviations: ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNi, angiotensin‐receptor‐neprilysin inhibitor; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CRT, cardiac resynchronization therapy; CV, cardiovascular; EF, ejection fraction; eGFR, estimated glomerular ...
Peter Moritz Becher, Felix Lindberg, Lina Benson, Camilla Hage, Ulf Dahlström, Stephan Rosenkranz, Francesco Cosentino, Giuseppe M.C. Rosano, Stefan Blankenberg, Paulus Kirchhof, Frieder Braunschweig, Lars H. Lund, Gianluigi Savarese   +12 more
wiley   +1 more source

Exploratory Evidence of a Gene–Smoking Interaction Involving MTR rs1805087 in Type 2 Diabetes Mellitus

ELECTROPHORESIS, EarlyView.
The graphical abstract illustrates how smoking interacts with an MTR rs1805087 gene variant to promote insulin resistance and β‐cell dysfunction through alterations in the folate cycle. PCR–RFLP genotyping and machine‐learning analysis support an exploratory assessment linking these combined factors to increased Type 2 diabetes risk in susceptible ...
João Pedro Costa Roriz, Leandro Prado Assunção, Nayane Soares de Lima, Diolina Gonçalves da Silva, Rodrigo da Silva Santos, Angela Adamski da Silva Reis   +5 more
wiley   +1 more source

HBCR_DMR: A Hybrid Method Based on Beta-Binomial Bayesian Hierarchical Model and Combination of Ranking Method to Detect Differential Methylation Regions in Bisulfite Sequencing Data. [PDF]

J Pers Med
Yassi M, Shams Davodly E, Hajebi Khaniki S, Kerachian MA.   +3 more
europepmc   +1 more source

Decision-theoretic designs for a series of trials with correlated treatment effects using the Sarmanov multivariate beta-binomial distribution. [PDF]

Biom J, 2018
Hee SW, Parsons N, Stallard N.
europepmc   +1 more source

Ketogenic diet fails to mitigate seizures and neuroinflammatory responses in a mouse model of virus‐induced epilepsy

Epilepsia, EarlyView.
Abstract Objective The ketogenic diet (KD) is a high‐fat, low‐carbohydrate intervention widely used to treat drug‐resistant epilepsy, thought to reduce seizures through a combination of metabolic, neuronal, and microbiota‐dependent mechanisms. Additionally, recent studies suggest that the anticonvulsant effects of KD require the gut microbiota, with ...
Casey H. Meili, Kaitlyn Allen, Daniel J. Doty, Sofia Del Fiol, Ana Beatriz DePaula‐Silva   +4 more
wiley   +1 more source

Modeling Risk Factors for Intraindividual Variability: A Mixed-Effects Beta-Binomial Model Applied to Cognitive Function in Older People in the English Longitudinal Study of Ageing. [PDF]

Am J Epidemiol
Parker RMA, Tilling K, Terrera GM, Barrett JK.   +3 more
europepmc   +1 more source

Application of the Marginal Beta-Binomial Model in Estimation the Overall Odds of Obesity Among Iranian Adults: Meta-Analysis Method. [PDF]

Int J Endocrinol Metab, 2019
Zeinolabedini A, Biglarian A, Seifi B, Bakhshi E.   +3 more
europepmc   +1 more source

Re‐evaluating impaired consciousness in temporal lobe epilepsy: The role of language dominance and network reorganization

Epilepsia, EarlyView.
Abstract Objective Temporal lobe epilepsy (TLE) frequently affects clinically‐classified ictal consciousness, which the 2025 International League Against Epilepsy (ILAE) classification operationalizes through clinical assessment of awareness and responsiveness.
Radheshyam Stepponat, Marc Berger, Laurin Schäfer, Laura Flamm, Kathrin Kollndorfer, Silvia Bonelli, Gregor Kasprian, Ekaterina Pataraia, Florian Ph. S. Fischmeister   +8 more
wiley   +1 more source

Impairment of ictal consciousness and psychosis in drug‐resistant focal epilepsy: A retrospective clinical cohort study

Epilepsia, EarlyView.
Abstract Objective Psychoses of epilepsy (POE) affect up to 13% of patients with focal epilepsy. Whereas interictal risk factors are well documented, ictal correlates of POE remain poorly characterized. We hypothesized that an impairment of ictal consciousness on the Consciousness Seizure Scale (CSS), would be associated with POE.
Alexis Tarrada, Coraline Hingray, Olivier Aron, Clélia Galmiche, Louis Maillard, Marco Mula, Bertrand De Toffol, Cédric Baumann, Sophie Baltassis   +8 more
wiley   +1 more source