Results 141 to 150 of about 692,862 (304)
, 1940 This is a black and white photo of Blocker standing next to a horse. The photo is taken from a low point of view, so Blocker is bending down to look at the camera.
Blocker, Fred A.
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Students Standing Around Talking
, 1940 This is a black and white photo of students standing around talking. This group is made up of about thirteen students. The group of students is in the middle ground of the photo.https://scholarsjunction.msstate.edu/ua-blocker-college/1304/thumbnail ...
Blocker, Fred A.
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
, 1940 This is a black and white photo of a man, Blocker, posing for a photo. Blocker is wearing a suit and bowtie, and he is standing in front of a closed in fireplace with one hand gesturing in front of him.
Blocker, Fred A.
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Khalid Abdulrahman Basamih,1 Asayil Yousef Almarjan,1 Faeqah Raja Allah Alharbi,1 Khalid Fawzi Salaemae,1 Sarah Naif Badahdah,1 Zuhaa Shihab Jaha,2 Anmar Jamil Mandourah3 1Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia ...
Jaha ZS +6 more
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Indian Journal of Dermatology, Venereology and Leprology, 2017 Neel, Prabha +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source