Results 131 to 140 of about 96,218 (256)

Blocking SUDEP With a Beta Blocker: Atenolol Reduces Seizure-Related Mortality. [PDF]

Epilepsy Curr
Buchanan GF.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Prophylaxis with diltiazem decreases arrhythmia rate when compared to beta-blocker following lobectomy. [PDF]

J Thorac Dis
Dyas AR, Stuart CM, Bata KE, Bronsert MR, Henderson WG, Kelleher AD, Barker AR, Randhawa SK, David EA, Mitchell JD, Meguid RA.   +10 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

The global trends and hotspots beta-blocker therapy in sepsis and septic shock: A bibliometric analysis based on CiteSpace and VOSviewer. [PDF]

Medicine (Baltimore)
Luo XY, Zhou J, Zheng J, Shi G, Li HL.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Long-term beta blocker prescribing after myocardial infarction in European primary care (PRACTITIONER). [PDF]

BMC Prim Care
Zangger M, Jungo KT, Adler L, Assenova R, Batic-Mujanovic O, Bracchitta L, Brütting C, Buczkowski K, Danilenko J, Erber P, Gefaell Larrondo I, Ilkov O, Javorska K, Jennings AA, Johannessen TR, Koskela T, Kurpas D, Lazić V, Mannheimer S, Moussa M, Seifert M, Taraj D, Torzsa P, Viegas Dias C, Zelko E, Gencer B, Streit S.   +26 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Beta-Blocker Therapy After Myocardial Infarction: A Systematic Review and Meta-Analysis of Contemporary Randomized Controlled Trials. [PDF]

Int J Mol Sci
Di Fusco SA, Matteucci A, Alonzo A, Castello L, Spinelli A, Aquilani S, Marino G, Fedele S, Nardi F, Colivicchi F.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source