Results 31 to 40 of about 692,862 (304)

Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling

, 2014
Grazia Daniela Femminella,1 Vincenzo Barrese,2,3 Nicola Ferrara,1,4 Giuseppe Rengo4 1Department of Translational Medical Sciences, Federico II University, Naples, Italy; 2Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II
Ferrara, N, Barrese V, Ferrara N, FERRARA, NICOLA, Rengo, G, Barrese, Vincenzo, FEMMINELLA, GRAZIA DANIELA, Femminella GD, Barrese, V, Rengo G, Femminella, GD, RENGO, GIUSEPPE   +11 more
core   +1 more source

Post-operative atrial fibrillation is influenced by beta-blocker therapy but not by pre-operative atrial cellular electrophysiology [PDF]

, 2006
<b>Introduction:</b> We investigated whether post-cardiac surgery (CS) new-onset atrial fibrillation (AF) is predicted by pre-CS atrial cellular electrophysiology, and whether the antiarrhythmic effect of beta-blocker therapy may involve pre ...
Redpath, C.J., Marshall, G.E., Russell, Julie A., Rankin, A.C., Rankin, Andrew C., Redpath, Calum J., Kane, K.A., Marshall, Gillian E., Pau, David, Kane, Kathleen A., Russell, J.A., Workman, Antony J., Norrie, J., Workman, A.J., Pau, D., Norrie, John   +15 more
core   +1 more source

THE CHOICE OF DRUG FROM THE STANDPOINT OF EVIDENCE-BASED MEDICINE: CASE STUDY OF BETA-BLOCKERS

Рациональная фармакотерапия в кардиологии, 2016
Basic principles of beta-blockers choice strategy are presented. Attention is focused on the facts concerning the evidence base for effects of various beta-blockers on the outcomes of cardiovascular diseases.
S. Yu. Martsevich, N. P. Kutishenko, Yu. V. Lukina   +2 more
doaj   +1 more source

Evaluation of Perioperative Beta-Blockers and Factors Associated with Postoperative Atrial Fibrillation in Cardiac Surgery: A Single Center Experience

Reviews in Cardiovascular Medicine, 2023
Background: Postoperative atrial fibrillation (AF) has a complex etiology, and beta-blockers are commonly recommended for its pharmacological prevention.
Alexandra Puscas, Marius M. Harpa, Klara Brinzaniuc, Hussam Al-Hussein, Hamida Al-Hussein, Cosmin Banceu, Carmen Opris, Claudiu Ghiragosian, Sanziana Flamind, Robert Balan, Septimiu Voidazan, Horatiu Suciu   +11 more
doaj   +1 more source

Preoperative beta-blocker in ventricular dysfunction patients: need a more granular quality metric

BMC Cardiovascular Disorders, 2021
Background The use of preoperative beta-blockers has been accepted as a quality standard for patients undergoing coronary artery bypass graft (CABG) surgery.
Hanwei Tang, Kai Chen, Jianfeng Hou, Xiaohong Huang, Sheng Liu, Shengshou Hu   +5 more
doaj   +1 more source

Beta-blocker-induced diabetes risk vs. the binding affinity for incretin receptors and other class B GPCRs.

, 2019
GUT-DOCK (Autodock VINA) results for selected beta-blockers (A). T2DM-related ranks were assigned according to [58, 61–66] and average GUT-DOCK results (see Table 3): 0 –compound 15, 1 –carvedilol, 2 –nebivolol, 3 –labetalol, 4—atenolol, 5 –metoprolol (1
Pawel Pasznik (384253), Dorota Latek (95762), Ewelina Rutkowska (2620405), Judyta Cielecka-Piontek (715035), Szymon Niewieczerzal (4017512)   +4 more
core   +1 more source

Beta-Blocker-Related Atrioventricular Conduction Disorders—A Single Tertiary Referral Center Experience

Medicina, 2022
Background and Objectives: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions.
Dragoș Traian Marius Marcu, Cristina Andreea Adam, Dan-Mihai Dorobanțu, Delia Lidia Șalaru, Radu Andy Sascău, Mircea Ovanez Balasanian, Liviu Macovei, Cătălina Arsenescu-Georgescu, Cristian Stătescu   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Beta Blockers and Melanoma

Open Access Macedonian Journal of Medical Sciences, 2019
Understanding the mechanisms of cancer immune-tolerance is one of the most important challenges. Several studies have demonstrated the potential anticarcinogenic effects of beta-blockers, in patients with prostate cancer, breast cancer, and melanoma.
Vojvodic, Aleksandra, Vojvodic, Petar, Vlaskovic-Jovicevic, Tatjana, Sijan, Goran, Dimitrijevic, Sanja, Peric-Hajzler, Zorica, Matovic, Dusica, Wollina, Uwe, Tirant, Michael, Thuong, Nguyen Van, Fioranelli, Massimo, Lotti, Torello   +11 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source