Results 41 to 50 of about 112,202 (290)

Effects of beta-blockers on archery performance, body sway and aiming behaviour

BMJ Open Sport & Exercise Medicine, 2021
Objectives This study aimed to determine the effect of selective (bisoprolol-5 mg) and non-selective (propranolol-40 mg) beta-blockers on archery performance, body sway and aiming behaviour.Methods Fifteen male archers participated in a randomised ...
Emin Ergen, Mesut Çelebi, Tahir Hazir, Ayşe Kin-Isler, Serdar Aritan, Volkan Daghan Yaylıoglu, Rustu Guner, Caner Acikada, Alpan Cinemre   +8 more
doaj   +1 more source

Beta-Blockers and Hypertension

Journal of the American College of Cardiology, 2009
Bangalore et al. ([1][1]) state that unlike results from post-myocardial infarction and congestive heart failure studies, a beta-blocker–induced low heart rate (HR) in hypertension is associated with an increase in death rate and cardiovascular (CV) events. This conclusion is highly misleading.
openaire   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The Potential Anti-remodeling Effect of Paroxetine After Myocardial Infarction May Be Blunted by Beta-Blockers

Frontiers in Cardiovascular Medicine, 2022
BackgroundLeft ventricular (LV) remodeling consists in maladaptive changes in cardiac geometry and function following an insult such as ST-segment elevation myocardial infarction (STEMI).
Oriol Iborra-Egea, Oriol Iborra-Egea, Alberto Aimo, Alberto Aimo, Nicola Martini, Carolina Galvez-Monton, Carolina Galvez-Monton, Silvia Burchielli, Giorgia Panichella, Claudio Passino, Claudio Passino, Michele Emdin, Michele Emdin, Antoni Bayes-Genis, Antoni Bayes-Genis, Antoni Bayes-Genis   +15 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Topical issues of beta-blockers use in various clinical situations

Медицинский совет, 2018
The article provides a review of the topical issues of beta-blockers use in the clinical practice. Attention of practitioners is drawn to the possibility of using these or other beta-blockers in various clinical situations. Some beta-blockers, especially
D. V. Nebieridze
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Use of beta-blockers and risk of serious upper gastrointestinal bleeding: a population-based case-control study

Therapeutic Advances in Gastroenterology, 2017
Background: Some studies indicate a reduced risk of serious upper gastrointestinal bleeding (UGIB) for users of beta-blockers, but the association remains to be confirmed in larger studies and characterized with respect to differences among beta-blockers.
Mette Reilev, Per Damkier, Lotte Rasmussen, Morten Olesen, Martin Thomsen Ernst, Rikke Mie Rishøj, Morten Rix Hansen, Anne Broe, Alexander Steenberg Dastrup, Maja Hellfritzsch, Sidsel Arnspang, Anton Pottegård, Jesper Hallas   +12 more
doaj   +1 more source