Results 51 to 60 of about 3,854,141 (349)

Beta blockers and their combinations in the management of hypertension

open access: yesSouth African Family Practice, 2012
Beta blockers have been prescribed for the treatment of primary hypertension for a very long time. Currently, it is doubtful whether this is still a good idea. In fact, many are of the opinion that beta blockers should be relegated to a fourth-line drug,
J.A. Ker
doaj   +1 more source

The association between beta-blocker use and chronic obstructive pulmonary disease risk, severity, and exacerbation

open access: yesMedical Journal of Babylon, 2021
Background: There is controversy about the role of beta-blockers in the number of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Hemin Khalid Saber
doaj   +1 more source

Evidence for down-regulation of beta-2-adreno-ceptors in cirrhotic patients with severe ascites [PDF]

open access: yes, 1986
The density and affinity of beta-2-adrenoceptors on mononuclear cells from peripheral blood were studied in fifteen patients with cirrhosis of different severity and in thirteen controls. There was no significant difference between cirrhotic patients and
AlexanderL. Gerbes   +22 more
core   +1 more source

Beta Blockers and Melanoma

open access: yesOpen Access Macedonian Journal of Medical Sciences, 2019
Understanding the mechanisms of cancer immune-tolerance is one of the most important challenges. Several studies have demonstrated the potential anticarcinogenic effects of beta-blockers, in patients with prostate cancer, breast cancer, and melanoma.
Vojvodic, Aleksandra   +11 more
openaire   +2 more sources

Exploring the equity of GP practice prescribing rates for selected coronary heart disease drugs: a multiple regression analysis with proxies of healthcare need [PDF]

open access: yes, 2005
Background There is a small, but growing body of literature highlighting inequities in GP practice prescribing rates for many drug therapies. The aim of this paper is to further explore the equity of prescribing for five major CHD drug groups and to ...
A Gibson   +77 more
core   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Use of Beta-Blockers as a First-Line Treatment for Primary Hypertension

open access: yesHearts
Background: Even though beta-blockers had been used as a first-line therapy for hypertension, since the late 1960s, the Eighth Joint National Committee, JNC 8, decided to recommend them no longer.
Maryam Izadi   +2 more
doaj   +1 more source

Self-reported and actual beta-blocker prescribing for heart failure patients: physician predictors.

open access: yesPLoS ONE, 2009
BackgroundBeta-blockers reduce mortality among patients with systolic heart failure (HF), yet primary care provider prescription rates remain low.ObjectiveTo examine the association between primary care physician characteristics and both self-reported ...
Sanjai Sinha   +3 more
doaj   +1 more source

Beta-blocker under-use in COPD patients [PDF]

open access: yes, 2017
Background: Cardiovascular (CVS) comorbidities are common in COPD and contribute significantly to morbidity and mortality, especially following acute exacerbations of COPD (AECOPD).
Lavender, Melanie   +4 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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