Results 131 to 140 of about 813,019 (233)

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

open access: yesThe FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast   +3 more
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

DISCRETE PHOSPHORYLATION GENERATES THE ELECTROPHORETIC HETEROGENEITY OF OVINE BETA-CASEIN

open access: yes, 1995
The heterogeneity of ovine beta-casein, apparent after discontinuous gel electrophoresis at alkaline pH and gel isoelectric focusing either by staining with Coomassie blue or immunoblotting, was investigated in detail.
FERRANTI, PASQUALE   +6 more
core  

Phi Beta Kappa, Alpha Chapter Records [PDF]

open access: yes, 1875
Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1875-1905.
Phi Beta Kappa   +1 more
core  

α‐1,3‐Glucan Is Required for Cell Wall Integrity and Full Virulence of Colletotrichum graminicola, but Not for Evasion of PAMP‐Triggered Immunity

open access: yesMolecular Microbiology, EarlyView.
Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase   +13 more
wiley   +1 more source

Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez   +14 more
wiley   +1 more source

The effect of milk constituents and crowding agents on amyloid fibril formation by κ-casein

open access: yes, 2016
When not incorporated into the casein micelle, κ-casein, a major milk protein, rapidly forms amyloid fibrils at physiological pH and temperature. In this study, the effects of milk components (calcium, lactose, lipids, and heparan sulfate) and crowding ...
David C Thorn (13674961)   +6 more
core   +1 more source

Phi Beta Kappa

open access: yes, 1905
Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1905-1928.
Phi Beta Kappa   +1 more
core  

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

A Comprehensive Evaluation of the Impact of Bovine Milk Containing Different Beta-Casein Profiles on Gut Health of Ageing Mice. [PDF]

open access: yesNutrients, 2020
Guantario B   +12 more
europepmc   +1 more source

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