Results 91 to 100 of about 3,797,625 (304)

Corporate tax rates in the EU: harmonisation and competition from the perspective of convergence analyses

Entrepreneurship and Sustainability Issues
Tax policy plays a key role in shaping the economic environment and the competitiveness of states within the common European market. Given the deepening economic integration within the EU, analysing tax system convergence is becoming increasingly ...
Šimon Uličný, Alena Andrejovská
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Rates of convergence for the posterior distributions of mixtures of Betas and adaptive nonparametric estimation of the density. [PDF]

In this paper, we investigate the asymptotic properties of nonparametric Bayesian mixtures of Betas for estimating a smooth density on [0, 1]. We consider a parametrization of Beta distributions in terms of mean and scale parameters and construct a ...
Rousseau, Judith
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A note on fractional stochastic convergence [PDF]

We show that a class of non-stationary stochastic processes exhibiting long-range dependence satisfies one definition of time series convergence proposed in the literature.
Roberto Guimaraes-Filho, Marcelo Mello
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Phi Beta Kappa: The Key Reporter Winter 2012-2013

, 2012
Announcement of the Beta of Nebraska chapter installation at Creighton University, p.
Phi Beta Kappa Society
core  

I rivali di Aristofane

, 2002
Partendo dalla recente pubblicazione di un volume curato da D. Harvey e J. Wilkins (The rivals of Aristophanes. Studies in Athenian Old Comedy, London 2000), Simone Beta discute sull'importanza dello studio dei frammenti comici per una conoscenza ...
BETA, SIMONE, Simone Beta
core   +1 more source

CONVERGENCE AND DIVERGENCE IN EUROPEAN UNION: EVIDENCE FOR BETA CONVERGENCE AMONG NEW EU MEMBER STATES [PDF]

Annals of the University of Oradea: Economic Science, 2013
: Convergence may be considered a central issue of the current economic literature, and not only, concentrating upon income distribution within different economies, but also focusing on different aspects of polarity and inequality that characterize ...
Ioana Sorina Mihuț, Mihaela Luțaș, ,   +3 more
doaj