Results 131 to 140 of about 3,797,625 (304)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

ANALYSIS OF CONVERGENCE WITHIN THE EUROPEAN UNION - SIGMA AND BETA CONVERGENCE [PDF]

open access: yes
Real convergence study began with the development of neoclassical models of growth and especially with the passage of econometric applications of these models. In this paper we present applications of indicators and patterns of convergence on the example
Begu Liviu-Stelian   +3 more
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Testing for Stochastic and Beta-convergence in Latin American Countries [PDF]

open access: yes
This paper uses time-series data from nineteen Latin American countries and the U.S. to test for income convergence using two existing definitions of convergence and a new testable definition of β-convergence.
Escobari, Diego
core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

La democrazia ateniese

open access: yes, 1993
Il volume è la traduzione italiana fatta da Simone Beta del libro di David L. Stockton "The Classical Athenian Democracy", pubblicato nel 1990 dalla Oxford University Press.
BETA, SIMONE
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Human capital spillovers, productivity and regional convergence in Spain [PDF]

open access: yes
This paper analyses the differential impact of human capital, in terms of different levels of schooling, on regional productivity and convergence. The potential existence of geographical spillovers of human capital is also considered by applying spatial ...
Raul Ramos   +2 more
core  

I poeti credevano nelle loro Muse? Atti della giornata di studio, Siena, 2 aprile 2003, a cura di S. Beta.

open access: yes, 2006
Nel corso dei secoli il ruolo delle Muse ha subito continue oscillazioni, passando da divine garanti dell’ispirazione artistica a figure superflue e fittizie, e viceversa. Eppure le Muse non sono sempre esistite.
Beta, Simone
core   +1 more source

Convergence of Regional Income Among Provinces in Kalimantan

open access: yesEkonomi dan Bisnis
The Indonesian economy shows that Kalimantan has an important role in the national economy, contributing 8.45% in 2014, placing it as the third largest after Java and Sumatra.
Fikrie Lazuardi Imaduddin, Bayu Kharisma
doaj  

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