Results 51 to 60 of about 3,797,625 (304)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Economic convergence of the Western Balkans towards the EU-15

open access: yesRevista Finanzas y Política Económica, 2019
This paper aims to analyze the beta convergence of Western Balkan countries towards the EU-15 Member States in the period 2004-2016, and two sub-periods: 2004-2008 and 2009-2013.
Sándor Gyula Nagy, Dzenita Siljak
doaj   +1 more source

Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome

open access: yesAGE, 2012
Deposition of aggregated amyloid beta (Aβ) is a major hallmark of Alzheimer’s disease (AD)—a common age-related neurodegenerative disorder. Typically, Aβ is generated as a peptide of varying lengths. However, a major fraction of Aβ peptides in the brains
L. De Kimpe   +6 more
semanticscholar   +1 more source

Economic Growth and Beta-Convergence Between EU and Ukraine

open access: yesIntellectual Economics, 2014
The empiric analysis of convergence processes between Ukraine and EU countries showed that the most spreading method of convergence presence in the rate of economic development is the reduction of the inequality of GDP per capita level among the countries groups.
Andrii Verstiak   +3 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Mind the Gap: The Efficiency Convergence of ASEAN Plus Three Economies

open access: yesJDE (Journal of Developing Economies), 2023
This study aims to examine the performance of technical efficiency convergence (Beta and Sigma convergences) of 10 ASEAN economies as well as other three main partners from East Asia, namely China, South Korea, and Japan for the years of 1990-2021, and ...
Mohammad Zeqi Yasin
doaj   +1 more source

Sigma Convergence Versus Beta Convergence: Evidence from U.S. County-Level Data [PDF]

open access: yesJournal of Money, Credit and Banking, 2003
In this paper we outline (i) why sigma-convergence may not accompany beta-convergence, (ii) discuss evidence of beta-convergence in the U.S., and (iii) use U.S. county-level data containing over 3,000 cross-sectional observations to demonstrate that sigma-convergence has not occurred at the county-level across the U.S., or within the vast majority of ...
Andrew T. Young   +2 more
openaire   +8 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Sigma Convergence versus Beta Convergence: Evidence from U.S. County-Level Data [PDF]

open access: yes
In this paper we outline (i) why sigma-convergence may not accompany beta-convergence, (ii) discuss evidence of beta-convergence in the U.S., and (iii) use U.S.
Levy, Daniel   +2 more
core   +2 more sources

Efflux Pumps Represent Possible Evolutionary Convergence onto the Beta Barrel Fold

open access: yesStructure, 2018
Summary There are around 100 varieties of outer membrane proteins in each Gram negative bacteria. All of these proteins have the same fold—an up-down βbarrel. It has been suggested that all membrane β-barrels excluding lysins are homologous.
M. W. Franklin   +5 more
semanticscholar   +1 more source

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