Results 101 to 110 of about 963,387 (281)

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

The effect of naltrexone as a carboplatin chemotherapy-associated drug on the immune response, quality of life and survival of dogs with mammary carcinoma. [PDF]

open access: yesPLoS ONE, 2018
The objective of this study was to evaluate the effect of low-dose naltrexone (LDN) as a carboplatin chemotherapy-associated drug in female dogs with mammary carcinoma in benign mixed tumors (MC-BMT) after mastectomy and to assess its association with ...
Marília Carneiro Machado   +8 more
doaj   +1 more source

The Effects of Exercise Stress on Equine Immune Function. [PDF]

open access: yes, 1992
The physiologic demands of exercise constitute a form of stress which is accompanied by modulation of immune responses. However, numerous studies in many different model systems have failed to clearly define the effects of exercise on immunity ...
Keadle, Tammie Lee
core   +2 more sources

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes   +6 more
wiley   +1 more source

The Effect of an Acute Swim Exercise Training Session on Changes in Se-rum Beta-endorphin and Cortisol Levels in Male Sprint Swimmers

open access: yesمجله دانشکده پزشکی اصفهان, 2011
Background: Most previous studies were concentrated on plasma beta-endorphin (ß-EP) and cortisol responses following sub-maximal or maximal exercise; however, little researches have been conducted on the efficacy of sports specialized exercise sessions ...
Mahnaz Sinaei   +4 more
doaj  

Effect of interferential current on perceived pain and serum cortisol associated with delayed onset muscle soreness [PDF]

open access: yes, 1997
The purpose of this study was to assess the effect of interferential current (IFC) on perceived pain and serum cortisol levels in subjects with delayed onset muscle soreness (DOMS).
NC DOCKS at The University of North Carolina at Greensboro   +1 more
core   +1 more source

Plasma levels of beta-endorphin and serotonin in response to specific spinal based exercises

open access: yesSouth African Journal of Physiotherapy, 2008
Exercises as the primary mode of treatment for low back disorders aim to achieve pain reduction, improvement in functional abilityand quality of life of for low back disorder sufferers.
O. Sokunbi, A. Moore, P. Watt
doaj   +1 more source

µ1-Opioid Rezeptor vermittelte Effekte von Beta-Endorphin auf die endotheliale und monozytäre Endothelin-1 und Stickstoffmonooxid Freisetzung [PDF]

open access: yes, 2009
Neben den klassischen kardiovaskulären Risikofaktoren sind psychosoziale Faktoren wie chronischer Stress oder Depression in der Genese der Atherosklerose von Bedeutung.
Barth, Stefan
core  

Efficacy of Procaine, With and Without Epinephrine, Compared to Lidocaine in Local Anesthesia for Calves Before Thermocautery Disbudding

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Within the European Union, the use of lidocaine in food‐producing animals is restricted due to concerns over human safety. This study compared the clinical effectiveness of procaine, with and without epinephrine, against lidocaine in pain alleviation during thermocautery disbudding in xylazine‐sedated calves.
Magdy Adam   +6 more
wiley   +1 more source

Acupuncture Analgesia in Total Thyroidectomy for Graves’ Disease: A Case Report

open access: yesJournal of Acupuncture Research, 2023
This study included a 42-year-old female farmer with a 2-year history of Graves’ disease who visited the hospital for a total thyroidectomy for her grade III goiter based on World Health Organization classification. Besides Hegu (LI4) and Neiguan (PC6)
Dong Phuong Tran
doaj   +1 more source

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