Beta-endorphin levels in both painful and painless diabetic peripheral neuropathy and its relations to pain characters and severity [PDF]
, 2017 Introduction. In the peripheral nervous system (PNS), beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both preand post-synaptic nerve terminals, primarily exerting their effect through presynaptic ...
Elbioumy, Azza A. +3 more
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Pharmacological modulation of beta-endorphin in rat peritoneal macrophages. [PDF]
, 1989 The neuropeptide beta-endorphin is present in cells of the immune system, i.e., lymphocytes and monocytes, and its expression can be induced by immunological stimuli.
A E Panerai, P Sacerdote
core +1 more source
Role of kappa‐opioid and mu‐opioid receptors in pruritus: Peripheral and central itch circuits
Experimental Dermatology, Volume 31, Issue 12, Page 1900-1907, December 2022., 2022 Abstract Modern genetic approaches in animal models have unveiled novel itch‐specific neural pathways, emboldening a paradigm in which drugs can be developed to selectively and potently target itch in a variety of chronic pruritic conditions. In recent years, kappa‐opioid receptors (KORs) and mu‐opioid receptors (MORs) have been implicated in both the ...
Brian S. Kim +5 more
wiley +1 more source
Study of humoral immunity indices for assessing physical exhaustion in sports
Медицинская иммунология, 2023 Studies of real opportunities for physical skills of athletes sufficiently depend on their adaptive potential for increasing physical loads. Extreme physical and psychoemotional loads may lead to overwork and decreased physical ability in professional ...
M. A. Myagkova +5 more
doaj +1 more source
Pain reactivity and plasma beta-endorphin in children and adolescents with autistic disorder. [PDF]
PLoS ONE, 2009 BACKGROUND:Reports of reduced pain sensitivity in autism have prompted opioid theories of autism and have practical care ramifications. Our objective was to examine behavioral and physiological pain responses, plasma beta-endorphin levels and their ...
Sylvie Tordjman +12 more
doaj +1 more source
Beta-endorphin 1-31 biotransformation and cAMP modulation in inflammation. [PDF]
PLoS One, 2014 A large body of evidence now exists for the immune cell expression, production, and the release of beta-endorphin (BE 1-31) within inflamed tissue. The inflammatory milieu is characterised by increased acidity, temperature and metabolic activity.
Asvadi NH +5 more
europepmc +2 more sources
Beta-Endorphin Receptors on Equine Lymphocytes: Relationship to Immune Function and Exercise. [PDF]
, 1990 Current evidence suggests that endogenous opioids are released in response to various stressors and that these opioids interact with cells of the immune system, and modulate immune function. However, data substantiating this are conflicting.
Hamra, Jena Gosselink
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Untersuchungen zur funktionellen Bedeutung von Proopiomelanocortin-Fragmenten : Nachweis spezifischer Bindungsstellen für beta H -Endorphin auf Keratinozyten und Vitronektin in Keratinozyten-Kulturen der Zellinie HaCaT [PDF]
, 2003 Eine gesteigerte Freisetzung des Opioidpeptids beta-Endorphin aus der Hypophyse ins Blut wurde häufig als Antwort des Organismus auf physischen oder psychischen Streß beobachtet.
Egeling, Katharina Thea
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Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brain [PDF]
, 1988 The total content and extent of processing of the [gamma]3MSH and [beta]-endorphin-containing N- and C-terminal domains of proopiomelanocortin were determined in the anterior and intermediate lobes of the pituitaries and in 11 regions of the brains of ...
Akil, Huda +6 more
core +1 more source
The acute effect of maximal exercise on plasma beta-endorphin levels in fibromyalgia patients. [PDF]
Korean J Pain, 2016 Background: This study aimed to investigate the effect of strenuous exercise on β-endorphine (β-END) level in fibromyalgia (FM) patients compared to healthy subjects. Methods: We enrolled 30 FM patients and 15 healthy individuals.
Bidari A +4 more
europepmc +2 more sources