Results 31 to 40 of about 11,956 (177)

Efficacy of deep brain stimulation of the subthalamic nucleus versus globus pallidus internus on sensory complaints

npj Parkinson's Disease
Pain control after deep brain stimulation (DBS) in Parkinson’s disease (PD) remains unclear. Following six months, subthalamic (STN)-DBS reduced sensory complaints related to parkinsonism and bodily discomfort, increasing central beta-endorphin level ...
Maria Gabriela S. Ghilardi, Ana Carolina P. Campos, Rubens G. Cury, Raquel C. R. Martinez, Rosana L. Pagano, Erich T. Fonoff   +5 more
doaj   +1 more source

Oral Self-Administration Of EtOH In Transgenic Mice Lacking Beta-Endorphin [PDF]

Impulse: The Premier Undergraduate Neuroscience Journal, 2007
EtOH modifies the production and/or release of endogenous opioid peptides, including -endorphin (Gianoulakis, 2004; Przewlocka et al., 1994; Schulz et al., 1980).
Stephani Allen, Kevin Karwan, Ashley Holloway, Sydney B. Williams, Judith E. Grisel   +4 more
doaj  

JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats

Molecular Pain, 2012
Background Proopiomelanocortin (POMC)-derived beta-endorphin1-31 from immune cells can inhibit inflammatory pain. Here we investigated cytokine signaling pathways regulating POMC gene expression and beta-endorphin production in lymphocytes to augment ...
Busch-Dienstfertig Melanie, Labuz Dominika, Wolfram Theresa, Vogel Nicole N, Stein Christoph   +4 more
doaj   +1 more source

Innervation of gonadotropin-releasing hormone neurons by peptidergic neurons conveying circadian or energy balance information in the mouse. [PDF]

PLoS ONE, 2009
Secretion of gonadotropin-releasing hormone (GnRH) produced in neurons in the basal forebrain is the primary regulator of reproductive maturation and function in mammals.
Daniel R Ward, Fiona M Dear, Ian A Ward, Susan I Anderson, Daniel J Spergel, Paul A Smith, Francis J P Ebling   +6 more
doaj   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Vernonia cinerea Less. supplementation and strenuous exercise reduce smoking rate: relation to oxidative stress status and beta-endorphin release in active smokers

Journal of the International Society of Sports Nutrition, 2010
Purpose The aim of this study was to evaluate the effects of Vernonia cinerea Less. (VC) supplementation and exercise on oxidative stress biomarkers, beta-endorphin release, and the rate of cigarette smoking.
Yankai Araya, Sriboonreung Thanyaluck, Pothongsunun Prapas, Pratanaphon Sainatee, Leelarungrayub Donrawee, Bloomer Richard J   +5 more
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Step into action: how reminders shape engagement in fitness apps

Economica, EarlyView.
Abstract Regular exercise offers well‐documented health benefits, and mobile applications are increasingly used to promote physical activity. In this study, we conduct a large‐scale randomized controlled trial with 20,187 users of the WeWard app in France to evaluate the effectiveness of different message framings and intervention durations on app ...
Beatrice Braut, Claire Mollier, Sarah Zaccagni   +2 more
wiley   +1 more source

Investigating variations of β-endorphin serum levels and pain caused by primary dysmenorrhea following a course of aerobic training with and without consumption of cumin supplement

مجله دانشگاه علوم پزشکی بیرجند, 2018
Background and Aim:  Dysmenorrheaorpainful menstruation of the most common complaints of the women's. Considering the effect of β-endorphin on reducing the pain of menstruation, the purpose of this study was to investigate changes in &beta ...
Mohadese Eidi Kakhki, Mohammad Esmaeil Afzalpour, Nahid Ghanbarzadeh, Ali Nadjafi Semnani   +3 more
doaj  

Episodic Ethanol Exposure in Adolescent Rats Causes Residual Alterations in Endogenous Opioid Peptides

Frontiers in Psychiatry, 2018
Adolescent binge drinking is associated with an increased risk of substance use disorder, but how ethanol affects the central levels of endogenous opioid peptides is still not thoroughly investigated.
Linnea Granholm, Lova Segerström, Ingrid Nylander   +2 more
doaj   +1 more source