Results 61 to 70 of about 757,965 (205)
The Evolution of Medications for Obesity Management
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley +1 more source
The Health Benefits of Exercise: Molecular and Cellular Mechanisms
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying +12 more
wiley +1 more source
Yoga as an Adjunct for Management of Opioid Dependence Syndrome: A Nine-Month Follow-Up Case Report
Opioid dependence syndrome (ODS) is a chronic relapsing remitting condition associated with significant impairment and mortality risk. Opioid substitution therapy is used worldwide, but long-term retention rates are low and there is risk of misuse and ...
Prateek Varshney +8 more
doaj +1 more source
ABSTRACT Aim Premature infants require interventions supporting comfort in the NICU and development after discharge. Therefore, this study examined the effects of maternal affectionate touch and lullaby singing on early comfort and of a developmental support programme on subsequent development.
Funda Güler, Hüsniye Çalişir
wiley +1 more source
Pain Management During Neonatal Blood Sampling: An Overview of Systematic Reviews
ABSTRACT This overview of systematic reviews aimed to identify effective pain management strategies for neonatal blood sampling. Searches were conducted in four databases from 2014 to April 2026. Eligible studies were systematic reviews including randomized or quasi‐randomized controlled trials assessing pain management in neonates during blood ...
Libby G. Lord +3 more
wiley +1 more source
Intra‐dorsal striatal corticosterone attenuated morphine‐induced CPP. GR and MR antagonists also attenuated morphine‐induced CPP. Morphine reduced DAT immunoreactivity, an effect prevented by CORT and antagonists. Distinct corticosteroid manipulations converged on similar reward and DAT outcomes.
Payman Raise‐Abdullahi +6 more
wiley +1 more source
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
The opioid polypeptide beta-endorphin is present in fetal blood but it is not clear whether its source is the fetus or the placenta. We therefore measured beta-endorphin in extracts of fetal femoral arterial and umbilical venous blood plasma in sheep by ...
JS Robinson (11115030) +6 more
core
Beta-endorphin-like immunoreactivity was measured in the pituitary and brain areas of rats and mice bearing tumors which secrete different pituitary hormones. The DCCXLIIId tumor secretes both luteinizing hormone and follicle stimulating hormone, and the
A. Panerai +3 more
core +1 more source
Background: Most previous studies were concentrated on plasma beta-endorphin (ß-EP) and cortisol responses following sub-maximal or maximal exercise; however, little researches have been conducted on the efficacy of sports specialized exercise sessions ...
Mahnaz Sinaei +4 more
doaj

