Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source
Ultraviolet Radiations Impact on the Skin‐Brain Axis: A Literature Review of our Current Knowledge
ABSTRACT Background Sunlight is essential for vitamin D synthesis and contributes to mood regulation, but it is also a major risk factor for skin aging and carcinogenesis. While the cutaneous and immune effects of ultraviolet radiation are well documented, its potential impact on brain function remains poorly understood.
Mariam Deriouich +2 more
wiley +1 more source
Hormonalis imprinting a kozponti idegrendszerben: okok es kovetkezmenyek. [PDF]
The notion of the perinatal "hormonal imprinting" has been published at first in 1980 and since that time it spred expansively. The imprintig develops at the first encounter between the developing receptor and the target hormone - possibly by the ...
Csaba, György
core +1 more source
BADREX: In situ expansion and coreference of biomedical abbreviations using dynamic regular expressions [PDF]
BADREX uses dynamically generated regular expressions to annotate term definition–term abbreviation pairs, and corefers unpaired acronyms and abbreviations back to their initial definition in the text.
Gooch, P.
core
The Role of Beta-Endorphin in Food Deprivation-Mediated Increases in Food Intake and Binge-Eating. [PDF]
Tolentino L, Iqbal A, Rahman S, Lutfy K.
europepmc +1 more source
Interaction of the Opiate and Neuroendocrine Systems [PDF]
Opiates are known to produce various physiological effects. Our understanding of these effects has been greatly increased by the discovery of the opiate receptor and the endogenous opioid peptides.
DeMaria, Jr, MD, Peter
core +1 more source
Epigenetic regulation of beta-endorphin synthesis in hypothalamic arcuate nucleus neurons modulates neuropathic pain in a rodent pain model. [PDF]
Tao Y +11 more
europepmc +1 more source
Daily L-leucine supplementation in novice trainees during a 12-week weight training program. [PDF]
PURPOSE: To investigate the effects of daily oral L-leucine ingestion on strength, bone mineral-free lean tissue mass (LTM) and fat mass (FM) of free living humans during a 12-wk resistance-training program. METHODS: Twenty-six initially untrained men (n
Ispoglou, T +3 more
core +1 more source
Beta-Endorphin and Oxytocin in Patients with Alcohol Use Disorder and Comorbid Depression. [PDF]
Roschina OV +9 more
europepmc +1 more source

