Results 31 to 40 of about 791,731 (159)

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

British Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović, Katarina Nastić, Miroslav Dinić, Emilija Brdarić, Uroš Pecikoza, Maja Tomić, Ana Micov   +6 more
wiley   +1 more source

Concentrations of free radicals and beta-endorphins in repeat breeder cows [PDF]

, 2007
Repeat breeding (RB) is one of the major problems that affect the reproductive efficiency and economy of milk production in dairy animals. So far, the etiopathogenesis of this pathology has not been defined completely.
RIZZO, ANNALISA, TRISOLINI C, MINOIA G, SCIORSCI, Raffaele Luigi, MANCA R   +4 more
core  

Perceived headache responses to exercise in patients with migraine: A cross‐sectional study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To characterize patient‐perceived headache responses to exercise in migraine and to identify associated clinical factors using a large‐scale registry. Background Regular exercise is often recommended for patients with migraine; however, it can also trigger migraine attacks.
Young‐Eun Gil, Mi Ji Lee
wiley   +1 more source

Central effects of beta-endorphins on glucose homeostasis in the conscious dog

, 1989
The effects of centrally administered beta-endorphins on glucose homeostasis in the conscious dog were studied. Intracerebroventricular administration of beta-endorphin (0.2 mg/h) caused a 70% increase in plasma glucose.
P. E. Williams, P. M. Radosevich, N. N. Abumrad, L. L. Brown, D. B. Lacy   +4 more
core   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Use of Platelet‐Rich Fibrin (PRF) on Palatal Wound Healing: A Narrative Review With Clinical Recommendations

Journal of Periodontal Research, EarlyView.
Based on the available evidence, the application of platelet‐rich fibrin (PRF) following free gingival graft (FGG) and subepithelial connective tissue graft (SCTG) harvesting appears to be a promising approach for enhancing wound healing, minimizing postoperative complications, and reducing analgesic consumption. ABSTRACT This clinical narrative review
Nima Farshidfar, Paras Ahmad, Nathan Estrin, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Untersuchungen zur funktionellen Bedeutung von Proopiomelanocortin-Fragmenten : Nachweis spezifischer Bindungsstellen für beta H -Endorphin auf Keratinozyten und Vitronektin in Keratinozyten-Kulturen der Zellinie HaCaT [PDF]

, 2003
Eine gesteigerte Freisetzung des Opioidpeptids beta-Endorphin aus der Hypophyse ins Blut wurde häufig als Antwort des Organismus auf physischen oder psychischen Streß beobachtet.
Egeling, Katharina Thea
core   +1 more source

Endotoxins and Biological Implications—Review

Public Health Challenges, Volume 5, Issue 4, December 2026.
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq, Nicolas Joly, Vincent Lequart, Patrick Martin, Marielba Morillo, Janne Rojas   +5 more
wiley   +1 more source