Results 201 to 210 of about 1,020,842 (327)

Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment

Aging Cell, EarlyView.
Local growth hormone (GH) is expressed and secreted by senescent cells in the aging human colon. GH triggers epithelial‐to‐mesenchymal transition and activates colon cell motility by regulating extracellular matrix proteins, inducing cytoskeleton rearrangement and altering cell motility protein phosphorylation.
Vera Chesnokova, Svetlana Zonis, Richard Ainsworth, Tugce Apaydin, Christian Wong Valencia, Elora C. Greiner, Robert Barrett, Arminja N. Kettenbach, Shlomo Melmed   +8 more
wiley   +1 more source

Production and characterization of .BETA.-galactosidase from lactose-fermenting yeasts.

, 1982
Takatoshi Itoh, Masaru Suzuki, Susumu Adachi   +2 more
openalex   +2 more sources

Conversion of vitamin D3 binding protein (group-specific component) to a macrophage activating factor by the stepwise action of beta-galactosidase of B cells and sialidase of T cells. [PDF]

, 1993
Naoki Yamamoto, R Kumashiro
openalex   +1 more source

TSP50 in Neural Stem Cells Regulates Aging‐Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota

Aging Cell, EarlyView.
TSP50 expression declines in the hippocampus of aged humans and mice. TSP50 deficiency in NSCs accelerates mouse aging, causing cognitive impairments and neuroinflammation. Restoring gut microbiota via FMT and TSP50 overexpression alleviates these phenotypes. Our study shows TSP50's critical role in aging and gut microbiota as a key mediator.
Xiaoli Li, Yuecong Chen, Zhuoyi Gao, Xiaoling Liu, Zhenbo Song, Feng Gao, Shuyue Wang, Chunlei Yu, Luguo Sun, Yanxin Huang, Lihua Zheng, Guannan Wang, Ying Sun, Jiawei Li, Xiaoguang Yang, Yongli Bao   +15 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme β-galactosidase from the genetically modified <i>Aspergillus niger</i> strain TOL. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Cavanna D, Liu Y.   +14 more
europepmc   +1 more source

Use of a siderophore detection medium, ethylene glycol degradation, and beta-galactosidase activity in the early presumptive differentiation of Nocardia, Rhodococcus, Streptomyces, and rapidly growing Mycobacterium species [PDF]

, 1991
Ellen H. Fiss, G. F. Brooks
openalex   +1 more source

Oxytocin Enhances Demethylation Through TET Enzyme Expression in Neurons of Aged Mice: Oxytocin as a Potential Antiaging Peptide

Aging Cell, EarlyView.
DNA methylation, mitochondrial dysfunction, inflammation, and senescence interact to form a vicious cycle. Here we report that oxytocin interrupts this vicious cycle by increasing TET2 expression, inducing DNA demethylation in aged neurons and raising plasma oxytocin levels, decreasing systemic inflammation.
Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shizu Hidema, Tomoyuki Ono, Shu Taira, Katsuhiko Nishimori, Heidi de Wet, Kenju Shimomura   +8 more
wiley   +1 more source

Immobilized β-galactosidase BgaC from Bifidobacterium adolescentis retains stability and activity during repeated cycles of use. [PDF]

Appl Microbiol Biotechnol
Mulualem DM, Dwan O, Kilcoyne M, O'Byrne C, Boyd A.   +4 more
europepmc   +1 more source

A novel proteolytic activity apparently initiating degradation of beta-galactosidase nonsense fragments in in vitro extracts of Escherichia coli.

, 1983
J L McKnight, Victor A. Fried
openalex   +1 more source

Studies on .BETA.-galactosidase. II. Purificaof .BETA.-of .BETA.-galactosidase from Macrophomina phaseoli and its enzymatic properties.

Chemical and Pharmaceutical Bulletin, 1976
Mamoru Sugiura, Mutsuko Suzuki, Tokiko Shimomura, Masanori Sasaki   +3 more
openaire   +4 more sources