Results 231 to 240 of about 77,546 (283)

Glia Regulate the Timing of Photoreceptor Differentiation in the Drosophila Visual System

Glia, Volume 74, Issue 2, February 2026.
Activation of EGFR signaling in sub‐retinal glia is required for timing photoreceptor differentiation in the Drosophila visual system. ILP3 and ILP6 are downstream targets of the EGFR pathway in sub‐retinal glia, which activate insulin signaling in photoreceptor precursor cells in the developing retina.
Qian Ren, Wen‐Tzu Chang, Yong Rao
wiley   +1 more source

Historical Control Analysis Demonstrates Greater Long-Term Reduction in Plasma Globotriaosylceramide (Gb3) by Venglustat Compared With Placebo or Agalsidase Beta in Male Patients With Classic Fabry Disease. [PDF]

Mol Genet Genomic Med
Germain DP, DasMahapatra P, Liu S, Deegan P, Ortiz A, Modur V, Wilcox WR.   +6 more
europepmc   +1 more source

WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A‐Dependent Regulation of TP53BP1

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Periodontitis, a chronic inflammatory disease, represents the primary cause of tooth loss in Chinese adults. Wilms tumor 1‐associating protein (WTAP) is a key component of the N6‐methyladenosine (m6A) methyltransferase complex, and has an unclear role in periodontitis pathogenesis, particularly concerning its regulatory functions in
Menglin Xiong, Tingting Wang, Yuan Liu
wiley   +1 more source

Urolithin A Alleviates Doxorubicin-Induced Senescence in Mesenchymal Stem Cells. [PDF]

Int J Mol Sci
Kalinin A, Zubkova E, Menshikov M, Parfyonova Y.   +3 more
europepmc   +1 more source

Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao, Zengguang Wang, Hanwen Chang, Yongjin Li, Binbin Wang, Xinfa Shao, Yuxin Zhang, Yixuan Lin, Xinlin Jia, Xianhao Zhou, Wentao Li, Dinghao Luo, Tanjun Deng, Xingzuan Lin, Chen Xu, Yaokai Gan, Dongyun Gu   +16 more
wiley   +1 more source

EIF4A3‐Induced Circular RNA circSnd1 Promotes Muscle Atrophy and Muscle Ageing by Stabilizing EEF1A1

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Muscle atrophy is a common complication of ageing, and many chronic conditions, lacks defined therapeutic interventions. It is still mostly unknown how circular RNAs contribute to muscle atrophy. Methods circRNA sequencing and quantitative real‐time PCR were performed to detect the changed circRNAs in muscle atrophy models and aged ...
Jin Li, Bing Jin, Yuwei Yan, Yuying Chen, Xiaohang Yin, Xinyi Ren, Qian Li, Jingying Chen, Siqi Wang, Tingting Yang, Yanan Zhang, Qiumeng Nie, Dongchao Lu, Ming Wu, Yan Yu, Lei Chen, Tarun Keswani, Guoping Li, Dragos Cretoiu, T. Scott Bowen, Junjie Xiao, Yongjun Zheng   +21 more
wiley   +1 more source

Therapeutic landscape of Fabry disease: advances and challenges from classical strategies to emerging therapies. [PDF]

Front Med (Lausanne)
Zhang M, Wang C.
europepmc   +1 more source

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1. [PDF]

J Inherit Metab Dis
Casazza K, Giugliani R, Regier DS, Jarnes J.   +3 more
europepmc   +1 more source

An effective system for senescence modulating drug development using quantitative high-content analysis and high-throughput screening. [PDF]

Commun Biol
Hu Y, Xue X, Han T, Li Y, Zhang T, Lu T, Zhang P.   +6 more
europepmc   +1 more source

Identification of <i>Streptococcus pneumoniae</i><i>-</i>Specific Proteins by Surface-Shaving Proteomics. [PDF]

J Proteome Res
Acha Alarcon L, Seguí G, Piñeiro-Iglesias B, Svetlicic E, Kondori N, Gomila M, Moore ERB, Karlsson R.   +7 more
europepmc   +1 more source