Standardized testing and written communication improve patient understanding of beta-lactam allergy testing outcomes: A multicenter, prospective study [PDF]
Background Historical penicillin allergy is commonly reported, but the lack of standardized allergy clinic practices may diminish the ability to delabel beta-lactam allergy appropriately.
Jacqueline Loprete +2 more
exaly +3 more sources
Beta-lactam allergy in the paediatric population. [PDF]
Abstract Beta-lactam allergy is commonly diagnosed in paediatric patients, but over 90% of individuals reporting this allergy are able to tolerate the medications prescribed after evaluation by an allergist. Beta-lactam allergy labels are associated with negative clinical and administrative outcomes, including use of less desirable ...
Wong T +5 more
europepmc +4 more sources
Overview of Beta-Lactam Allergy and the Role of the Pharmacist in Management
Unverified beta-lactam allergies are a substantial public health problem, as the majority of patients labeled as beta-lactam allergic do not have clinically significant allergies that may hinder the use beta-lactam therapy when indicated.
Nicole Bradley +2 more
doaj +3 more sources
Utility of beta-lactam allergy assessment in patients receiving vancomycin for surgical prophylaxis [PDF]
Background: Beta-lactam antibiotics are first-line agents for most patients receiving antimicrobial prophylaxis in surgical procedures. Despite evidence showing low cross-reactivity between penicillins and cephalosporins, patients with beta-lactam ...
Kendall J. Tucker +6 more
doaj +2 more sources
Beta-lactam allergy in adults with cystic fibrosis [PDF]
Allergic reactions to one or more beta-lactam antibiotic can pose a management problem in patients with cystic fibrosis (CF), and may limit antibiotic choice.The aim of this study was to assess the prevalence of allergy to anti-pseudomonal beta-lactam antibiotics in an adult CF centre and to assess variables, which may contribute to the development of ...
Judith Burrows +2 more
exaly +5 more sources
Differences in beta-lactam and penicillin allergy: Beyond the West and focusing on Asia-Pacific
Beta-lactam (BL) antibiotic “allergy” labels are common, but often overdiagnosed. Although much research has been focused on the BL allergy and the delabelling process in the West, studies from other parts of the world remain sparse. This review outlines
Hugo W.F. Mak +4 more
doaj +3 more sources
Genetic associations in beta-lactam allergy [PDF]
Immediate reactions to beta-lactams (BLs) are the most common allergic reactions against drugs and can be life-threatening. The genetic risk factors influencing these reactions are poorly known, except those, which were previously identified as predictors of atopy and inflammation. Two polymorphisms of nucleotide-binding oligomerization domain 2 (NOD2),
Gueant J +5 more
europepmc +3 more sources
Management and Implications of Beta-Lactam Allergies [PDF]
Beta-lactam antibiotics are essential components in the current antimicrobial treatment strategy, playing a crucial role in ambulatory patients and hospitalized patients. Despite their prominent therapeutic index, the use of beta-lactam can lead to adverse effects, with allergic reactions being the most concerning because of their severity ...
Esteban Zavaleta‐Monestel +4 more
openalex +3 more sources
Clinical history in suspected cases of immediate allergy to beta-lactam
Background: Mislabeling patients as allergic to beta lactams poses an increased risk of morbidity, healthcare costs, and even mortality. This study aimed to define the accuracy of medical history, taken by a specialist, in diagnosing immediate reaction ...
Yossi Rosman +5 more
doaj +3 more sources
1267. Implementation and Outcomes of Beta-lactam Allergy Management Protocol at a Comprehensive Cancer Center [PDF]
Sohanabanu I. Khalak +9 more
europepmc +3 more sources

