Antibiotics, 2023 Beta-lactams are an important family of antibiotics used to treat infections and are commonly used in critically ill patients. Optimal use of these drugs in the intensive care unit (ICU) is important because of the serious complications from sepsis ...
Amy Legg +2 more
exaly +3 more sources
Overview of Beta-Lactam Allergy and the Role of the Pharmacist in Management
Allergies, 2021 Unverified beta-lactam allergies are a substantial public health problem, as the majority of patients labeled as beta-lactam allergic do not have clinically significant allergies that may hinder the use beta-lactam therapy when indicated.
Nicole Bradley, Dana Weinstein
exaly +3 more sources
PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance [PDF]
Microorganisms, 2018 β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Thaina M. da Costa +3 more
doaj +4 more sources
Promising Future of Novel Beta-Lactam Antibiotics Against Bacterial Resistance [PDF]
Drug Design, Development and TherapySaeed M Tayeb,1 Jaser A Alharbi,1 Bushra B Alattas,1 Dana M Alotaibi,1 Nawaf M Althibaiti,1 Jaser F Alharbi,1 Ahmad E SafirAldeen,1 Ibrahim R Alqurashi,1 Saad M Wali2 1Pharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University ...
Tayeb SM +8 more
doaj +2 more sources
Digital five-step questionnaire to enhance standard perioperative prophylaxis in surgical patients with reported allergy to beta-lactam-antibiotics [PDF]
Antimicrobial Stewardship & Healthcare EpidemiologyBackground: Most self-reported beta-lactam antibiotic (BLA) allergies are inaccurate. This study evaluated a digital tool designed to reassess beta-lactam allergies and enable the use of standard perioperative antibiotic prophylaxis (PAP) without the ...
Daniel Röder +5 more
doaj +2 more sources
Impact of beta-lactam allergy labels on antibiotic prophylaxis and surgical site infections after cesarean section; a retrospective study [PDF]
Antimicrobial Resistance and Infection ControlBackground Reported beta-lactam allergies often lead to avoidance of first-line antibiotics and may increase surgical complications. Cesarean sections (CSs), where prophylactic antibiotics are universally administered, offer a unique setting to assess ...
Mudrik-Zohar Hadar +5 more
doaj +2 more sources
Impact of beta-lactam allergy labels on bone marrow transplant patients [PDF]
Antimicrobial Stewardship & Healthcare EpidemiologyBackground: Approximately 95% of patients with a beta-lactam allergy noted in their medical record are not truly allergic when tested. These patients may unnecessarily avoid first-line antibiotics, resulting in increased treatment failure, higher costs ...
Benjamin M. Haxby +5 more
doaj +2 more sources
Daptomycin versus beta-lactam based therapy for the treatment of enterococcal endocarditis and other endovascular infections: a retrospective cohort study [PDF]
BMC Infectious DiseasesBackground Daptomycin has a favorable efficacy and safety profile against enterococcal infections, but it is currently a last line treatment for enterococcal infective endocarditis (EIE) due to limited evidence supporting its use.
Vindya Perera +4 more
doaj +2 more sources
Pengolahan Air Limbah Betalaktam Menggunakan Reagen Kaporit, PAC, dan Alum Sulfat
Jurnal Serambi Engineering, 2021 Beta lactam antibiotics are pollutant in water bodies such as lakes and rivers. Beta lactam rings may have a negative impact on living beings in lakes and rivers. Beta lactam rings also cause resistance or bacterial resistance to antibiotics.
Gede H. Cahyana +2 more
doaj +1 more source
Endopeptidase-mediated beta lactam tolerance. [PDF]
PLoS Pathogens, 2015 In many bacteria, inhibition of cell wall synthesis leads to cell death and lysis. The pathways and enzymes that mediate cell lysis after exposure to cell wall-acting antibiotics (e.g.
Tobias Dörr +2 more
doaj +1 more source