Results 41 to 50 of about 637,109 (288)
Oxidant-Scavenging Activities of Beta-Lactam Agents [PDF]
, 1998 peer reviewedThe relative antioxidant effect of ampicillin, ceftazidime, ceftriaxone, and cefuroxime on oxygen-reactive species was examined in vitro using stimulated human polymorphonuclear neutrophils.
Jadoul, L. +4 more
core +1 more source
Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the ‘Maximum Tolerable Dose’
Antibiotics, 2022 The surge in antimicrobial resistance and the limited availability of new antimicrobial drugs has fueled the interest in optimizing antibiotic dosing. An ideal dosing regimen leads to maximal bacterial cell kill, whilst minimizing the risk of toxicity or
Sofie A. M. Dhaese +2 more
doaj +1 more source
Advanced Science, EarlyView.High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott +5 more
wiley +1 more source
Beta-lactam and metronidazole resistance in the Bacteroides fragilis group [PDF]
, 2001 The Bacteroides fragilis group organisms are anaerobic gram-negative bacilli. Ten species are currently included in this group. Members of the B. fragilis group are the major constituents of the normal colonic microflora and the most commonly encountered
Hong Fang (43040)
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PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance
Microorganisms, 2018 β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Thaina M. da Costa +3 more
doaj +1 more source
Drugs in Context, 2022 Antimicrobial resistance is a global public health threat due to its associated increase in mortality, and the most appropriate treatment algorithms for resistant and persistent Gram-positive and Gram-negative infections have yet to be elucidated. Whilst
Alireza FakhriRavari +4 more
doaj +1 more source
Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions
Advanced Science, EarlyView.Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han +11 more
wiley +1 more source
The outpatient use of beta lactam antibiotics in Montenegro before the introduction of new reform strategy on drug market [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2006 Introduction: The study represents the first investigation of outpatient use of beta lactam antibiotics in Montenegro carried out in accordance with internationally approved methodology (DDD/ATC).
Duborija-Kovačević Nataša
doaj +1 more source
A Strong Lewis Acidic Diethylsilylium Catalyst for Direct Sulfonamidation of Challenging Ketones
Advanced Science, EarlyView.Low‐substitution‐order silylium ions (R2HSi+) exhibit exceptional Lewis acidic activity. We report diethylsilylium‐catalyzed reductive sulfonamidation of functionalized ketones to access β‐amino esters. The in situ generated ion pair shows enhanced reactivity, with diethylsilane serving as both reductant and precatalyst. The developed protocol proceeds
Woo Hee Kim +5 more
wiley +1 more source
Beta-lactam resistance in Campylobacter [PDF]
, 2011 Resistance to β-lactam antibiotics in Campylobacter is often associated with the production of a β-lactamase; to date the genomically encoded bla\(_{OXA-61}\) and the closely related cj0299 are the only described β-lactamase genes of Campylobacter ...
Stones, Leanne
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