Results 31 to 40 of about 89,494 (296)

Historical Review of the Penicillin and Related Compounds (β – Lactams)

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
In spite of  the old age of beta lactam, they continue to provide good health and preventing human diseases by virtue of  industrial production and discoveries of small new beta-lactam group of secondary metabolite.
Luma Salman Abd
doaj   +1 more source

Beta-lactam antibiotic test doses in the emergency department

open access: yesWorld Allergy Organization Journal, 2020
Background: Facilitating beta-lactam antibiotic use in patients reporting beta-lactam allergies in acute care settings is important to individual patient outcomes and public health; however, few initiatives have targeted the Emergency Department (ED ...
Michelle Maguire   +9 more
doaj   +1 more source

Setting the Beta-Lactam Therapeutic Range for Critically Ill Patients: Is There a Floor or Even a Ceiling?

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Beta-lactam antibiotics exhibit high interindividual variability in drug concentrations in patients with critical illness which led to an interest in the use of therapeutic drug monitoring to improve effectiveness and safety.
Erin F. Barreto, PharmD, MSc   +5 more
doaj   +1 more source

Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]

open access: yes, 2010
More than half of all currently used antibiotics belong to the beta-lactam group, but their clinical effectiveness is severely limited by antibiotic resistance of microorganisms that are the causative agents of infectious diseases. Several mechanisms for
A. A. Medeiros   +127 more
core   +1 more source

Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study

open access: yesImplementation Science Communications, 2021
Background Beta-lactams (i.e., penicillins, cephalosporins, carbapenems, monobactams) are the most widely used class of antibiotics in critically ill patients.
Erin F. Barreto   +10 more
doaj   +1 more source

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

open access: yes, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania   +19 more
core   +1 more source

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

open access: yes, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A   +173 more
core   +4 more sources

Incidence of acute kidney injury in critically ill patients receiving vancomycin with concomitant piperacillin-tazobactam, cefepime, or meropenem [PDF]

open access: yes, 2019
Critically ill patients are frequently treated with empirical antibiotic therapy, including vancomycin and -lactams. Recent evidence suggests an increased risk of acute kidney injury (AKI) in patients who received a combination of vancomycin and ...
Blevins, Adam M   +5 more
core   +2 more sources

Molecular characterization of ESBL-producing Shigella sonnei isolates from patients with bacilliary dysentery in Lebanon

open access: yesJournal of Infection in Developing Countries, 2009
Background: Emergence of extended-spectrum -lactamases (ESBLs) in Shigella species imparting resistance to third-generation cephalosporins is a growing concern worldwide. The aim of this study is to molecularly characterize the newly emerging beta-lactam
Ahmad H. Sabra   +6 more
doaj   +1 more source

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

open access: yes, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown   +27 more
core   +2 more sources

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