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Mechanisms of resistance to beta-lactam antibiotics.
Scandinavian journal of infectious diseases. Supplementum, 1991The use of new beta-lactam antibiotics has led to selection of novel forms of resistance. Newer-generation cephalosporins, ureidopenicillins and monobactams, but not carbapenems (e.g. imipenem), are labile to Class I chromosomal beta-lactamases and tend to select mutants of E. cloacae and P.
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Trends in beta-lactam resistance among Enterobacteriaceae
1998beta-Lactam resistance among Enterobacteriaceae is related primarily to the emergence of novel beta-lactamases. The class A extended-spectrum beta- lactamases hydrolyze extended-spectrum beta-lactams and are inhibited by clavulanic acid. These beta-lactamases are divided in two groups: TEM and SHV derivatives and non-TEM and non-SHV extended-spectrum ...
P. Nordmann +17 more
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Beta-lactam resistance in Neisseria spp
The Lancet, 1990N. Cimolai, E. Bryce
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Mechanisms of beta-lactam resistance in anaerobic bacteria.
Reviews of Infectious Diseases, 1986C. Nord
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[Mechanisms of resistance to beta-lactam antibiotics].
Infection, 1994Beta-lactam antibiotics share the structural feature of a beta-lactam ring. This feature is responsible for inhibition of bacterial cell wall synthesis. The target molecules are peptidoglycan cross-linking enzymes (e.g. transpeptidases and carboxypeptidases) which can bind beta-lactam antibiotics (penicillin binding proteins, PBP). Bacterial cell death
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Resistance to Beta-Lactam Antimicrobial Agents
Journal of Infectious Disease Pharmacotherapy, 1995openaire +1 more source
Resistance mechanisms against beta-lactam anti biotics
2015Beta-laktam antibiyotikler günümüzde en sık kullanılan antibiyotik türevlerinin başında gelir. Bu antibiyotikler "penisiline bağlanan proteinler" (PBP) adı verilen enzimler üzerinde etki göstererek bakterilerin hücre duvar sentezini inhibe eder.
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