Clinical and imaging predictors of late‐onset GM2 gangliosidosis: A scoping review
Annals of Clinical and Translational Neurology, Volume 11, Issue 1, Page 207-224, January 2024.Abstract Objective Late‐onset GM2 gangliosidosis (LOGG) subtypes late‐onset Tay‐Sachs (LOTS) and Sandhoff disease (LOSD) are ultra‐rare neurodegenerative lysosomal storage disorders presenting with weakness, ataxia, and neuropsychiatric symptoms. Previous studies considered LOTS and LOSD clinically indistinguishable; recent studies have challenged this.
Neha P. Godbole +7 more
wiley +1 more source
Changes in the Gut Metabolic Landscape Drive Inflammation-Associated Dysbiosis and Host Responses [PDF]
, 2023 The file named "HUGHES-PRIMARY-2022-1.pdf" is the primary dissertation file. Three (3) supplemental files are also available and are referenced in the dissertation file as appendices; the files are Microsoft Excel documents and may be viewed individually.
Hughes, Elizabeth Rose
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Akkermansia muciniphila and Alcohol‐Related Liver Diseases. A Systematic Review
Molecular Nutrition &Food Research, Volume 68, Issue 2, January 2024.Proposed mechanisms of A. muciniphila in excessive alcohol consumption: at the intestinal level, by protecting the mucus layer, producing metabolites, increasing diversity and, reducing the gut permeability and translocation of pathogens; at the hepatic level, by down‐regulating markers of inflammation and oxidative stress, and at the systemic level ...
Lydie Sparfel +4 more
wiley +1 more source
Mediators of Inflammation, Volume 2024, Issue 1, 2024.Objective. Fetal growth restriction (FGR) is a significant contributor to negative pregnancy and postnatal developmental outcomes. Currently, the exact pathological mechanism of FGR remains unknown. This study aims to utilize multiomics sequencing technology to investigate potential relationships among mRNA, gut microbiota, and metabolism in order to ...
Hui Tang +6 more
wiley +1 more source
Purification and characterization of thermostable beta-N-acetylhexosaminidase of Bacillus stearothermophilus CH-4 isolated from chitin-containing compost [PDF]
Applied and Environmental Microbiology, 1994 Thermostable exochitinase was purified to homogeneity from the culture fluid of Bacillus stearothermophilus CH-4, which was isolated from agricultural compost containing shrimp and crabs. The enzyme was a single polypeptide with a molecular mass of 74 kDa, and the N-terminal amino acid sequence was WDKVGVTDLI ISLNIPEADAVVVGMTLQLQALHLY.
K, Sakai +4 more
openaire +2 more sources
Brain lipid profiling of triply mouse model with the deficiencies of sialidase neu1, neu4 and β-hexosaminidase a enzymes [PDF]
, 2011 Thesis (Master)--Izmir Institute of Technology, Molecular Biology and Genetics, Izmir, 2011Includes bibliographical references (leaves: 41-61)Text in English; Abstract: Turkish and Englishxi, 61 leavesTay-Sachs disease is a severe lysosomal storage ...
Pekmezci, Zehra Kevser
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Analysis of cell surface characteristics of human cancer cell lines using derivatized agarose beads [PDF]
, 2003 The surface characteristics of cancer cells play an important role in altered behavior leading to invasion and metastasis. Furthermore, many cancer treatments focus on the surface properties of these cells.
Khatibi, David
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Subcellular localization and functional characterization of the Arabidopsis thaliana homologue of cellular repressor of E1A-stimulated genes (CREG) [PDF]
, 2009 „Cellular repressor of E1A-stimulated genes“ (CREG) ist ein Phosphoglykoprotein in den Lysosomen tierischer Zellen. Ziel dieser Arbeit war es , Einsicht in die subzelluläre Lokalisation und Funktion von CREG in pflanzlichen Zellen zu erlangen.
Ivanova, Christa Ivova
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Identificação de novos potenciais inseticidas e antivirais utilizando ferramentas computacionais e banco de dados de produtos naturais [PDF]
, 2021 Secondary metabolites are an important source of compounds for pest management, providing an alternative to replace synthetic, persistent and toxic insecticides. Among the classes of natural products, the terpenes stand out, which cover a wide variety of
Rodrigues, Gabriela Cristina Soares
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Identification of the Mechanisms Through Which Botanicals Attenuate Pathogenesis of Human Diseases [PDF]
, 2018 Plant products have been used for a long time in treatment of diseases. In fact, more than half of approved medicines are derived from plants or other natural products.
Alharris, Esraah
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