Results 131 to 140 of about 11,128,191 (264)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

SOLVING ASSIGNMENT PROBLEM WITH LINGUISTIC COSTS

open access: yesJournal of New Theory, 2017
– The purpose of this paper is to solve an assignment problem with linguistic costs/ times. In this paper, an assignment problem has been considered whose costs/times relating to the problem are linguistic variables and its solution methodology has been ...
Laxminarayan Sahoo, Santanu Kumar Ghosh
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

I poeti credevano nelle loro Muse? Atti della giornata di studio, Siena, 2 aprile 2003, a cura di S. Beta.

open access: yes, 2006
Nel corso dei secoli il ruolo delle Muse ha subito continue oscillazioni, passando da divine garanti dell’ispirazione artistica a figure superflue e fittizie, e viceversa. Eppure le Muse non sono sempre esistite.
Beta, Simone
core   +1 more source

Old-Iniquity : (Goethes "Faust" und Hermann Türck) / Ottomar Beta

open access: yes, 1908
OLD-INIQUITY : (GOETHES "FAUST" UND HERMANN TÜRCK) / OTTOMAR BETA Old-Iniquity : (Goethes "Faust" und Hermann Türck) / Ottomar Beta (1) Cover (1) Old-Iniquity ...
Beta, Ottomar
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Beta-Estradiol Hormone Application to Increase Salt Tolerance of Different Potato Genotypes (Solanum tuberosum L.)

open access: yesIkufīziyuluzhī-i Giyāhān-i Zirā̒ī
This experiment was performed to investigate the effect of beta estradiol hormone application on increasing salinity stress tolerance of different potato genotypes in a factorial split plot experiment based on a randomized complete block design with ...
Fahimeh Jidar   +4 more
doaj  

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