Results 111 to 120 of about 1,352,947 (309)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Nested chain movement of length 1 of beta number in James abacus diagram [PDF]

open access: yes, 2016
James abacus diagram is a graphical representation for any partition µ of a positive integer t.One way of producing the diagram is by using beta number with the special number of even columns e, where e 2.This paper constructs a new method for ...
Ahmad, Nazihah   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Is variation in copy number of the human beta defensin gene cluster associated with preterm birth? [PDF]

open access: bronze, 2015
CP James   +7 more
openalex   +1 more source

Synthesis of new α,β-unsaturated butenolides

open access: yesBulletin of the Chemical Society of Ethiopia, 2010
A number of new &gama;-substituted α,β-unsaturated butenolides have been synthesized by the condensation of phenols with β-(3-nitrobenzoyl)acrylic acid and β-(4-methyl-3-nitrobenzoyl)acrylic acid.
Veena Joshi, R.P. Chamoli
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Mach number and plasma beta dependence of the ion temperature perpendicular to the external magnetic field in the transition region of perpendicular collisionless shocks

open access: yesAIP Advances, 2019
Ion temperature anisotropy is a common feature for (quasi-)perpendicular collisionless shocks. By using two-dimensional full particle simulations, it is shown that the ion temperature component perpendicular to the shock magnetic field at the shock foot ...
Ryo Yamazaki   +3 more
doaj   +1 more source

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