Results 101 to 110 of about 11,128,191 (264)

Synthesis of new α,β-unsaturated butenolides

open access: yesBulletin of the Chemical Society of Ethiopia, 2010
A number of new &gama;-substituted α,β-unsaturated butenolides have been synthesized by the condensation of phenols with β-(3-nitrobenzoyl)acrylic acid and β-(4-methyl-3-nitrobenzoyl)acrylic acid.
Veena Joshi, R.P. Chamoli
doaj  

Mach number and plasma beta dependence of the ion temperature perpendicular to the external magnetic field in the transition region of perpendicular collisionless shocks

open access: yesAIP Advances, 2019
Ion temperature anisotropy is a common feature for (quasi-)perpendicular collisionless shocks. By using two-dimensional full particle simulations, it is shown that the ion temperature component perpendicular to the shock magnetic field at the shock foot ...
Ryo Yamazaki   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Derivatives of the Incomplete Beta Function [PDF]

open access: yes
The incomplete beta function is defined as where Beta(p, q) is the beta function. Dutka (1981) gave a history of the development and numerical evaluation of this function. In this article, an algorithm for computing first and second derivatives of Ix,p,q
James F. Robinson-Cox, Robert J. Boik
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

ON THE BETA-NUMBER OF THE CORONAS GRAPHS

open access: yesON THE BETA-NUMBER OF THE CORONAS GRAPHS
The beta-number of a graph G is the smallest positive integer n for which there exists an injective function f : V(G)→{0,1,...,n} such that each uv ∈ E(G) is labeled f(u)-f(v) and the resulting set of edge labels is {c,c+1,...,c+E(G) -1} for some positive integer c. The beta-number of G is +∞ if there exists no such integer n.
openaire   +1 more source

[Stammbuch Beta Khampf] [PDF]

open access: yes
[STAMMBUCH BETA KHAMPF] [Stammbuch Beta Khampf] ( - ) Cover ( - ) Einträge Bl. 1 - 2 ( - ) Titelblatt, Bl. 3 ( - ) Einträge Bl. 4 - 10 ( - ) Einträge Bl. 11 - 20 ( - ) Einträge Bl. 21 - 30 ( - ) Einträge Bl. 31 -
Khampf, Beta
core  

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