Results 101 to 110 of about 1,352,947 (309)

TeV-scale Lepton Number Violation: Connecting Leptogenesis, Neutrinoless Double Beta Decay, and Colliders [PDF]

open access: green, 2021
Julia Harz   +3 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

331 Validation of a Novel CSF-Based Biomarker of Mitochondrial Function

open access: yesJournal of Clinical and Translational Science
OBJECTIVES/GOALS: Determine the exosome mitochondrial DNA (mtDNA) copy number in cerebrospinal fluid (CSF) as a measure of neuronal mitochondrial integrity in patients with subarachnoid hemorrhage (SAH).
Dhanushki Abeykoon   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Existence of solutions for semilinear problems with prescribed number of zeros on exterior domains

open access: yesElectronic Journal of Differential Equations, 2016
In this article we prove the existence of an infinite number of radial solutions of $\Delta(u)+f(u)=0$ with prescribed number of zeros on the exterior of the ball of radius R>0 centered at the origin in $\mathbb {R}^N$ where f is odd with f0 on ...
Janak Joshi, Joseph Iaia
doaj  

THE EFFECT OF BETA GLUCAN OF SACCHAROMYCES CEREVISAE ON THE INCREASE OF THE NUMBER OF BRAIN CELLS IN SUBSTANTIA NIGRA BRAIN OF PARKINSON’S WISTAR STRAIN RAT (RATTUS NORVEGICUS) MODEL INDUCED WITH ROTENONE

open access: yesMalang Neurology Journal, 2015
ackground and aims. One of many neurodegenerative diseases afflicting the elderly is Parkinson. Beta glucan from Saccharomyces cerevisae is very potential to be used as a regenerative therapy of Parkinson's disease.
Masruroh Rahayu   +2 more
doaj   +1 more source

Bounding the joint numerical range of Pauli strings by graph parameters

open access: yes, 2023
The interplay between the quantum state space and a specific set of measurements can be effectively captured by examining the set of jointly attainable expectation values. This set is commonly referred to as the (convex) joint numerical range.
Schwonnek, René   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

open access: yesMolecular Metabolism, 2017
Background: Plasma insulin levels are predominantly the product of the morphological mass of insulin producing beta cells in the pancreatic islets of Langerhans and the functional status of each of these beta cells.
Chunguang Chen   +4 more
doaj   +1 more source

Code CUGEL: A code to unfold Ge(Li) spectrometer polyenergetic gamma photon experimental distributions [PDF]

open access: yes
A FORTRAN code was developed for the Univac 1108 digital computer to unfold lithium-drifted germanium semiconductor spectrometers, polyenergetic gamma photon experimental distributions.
Born, U., Steyn, J. J.
core   +1 more source

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