Results 81 to 90 of about 1,352,947 (309)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Dynamics of c-kit immunopositive pancreatic beta cells influenced by exogenous factors or endogenous pathology

open access: yesZaporožskij Medicinskij Žurnal
Mechanisms of beta-endocrinocyte differentiation involving c-kit may be associated with a number of processes, including signaling pathways and regulatory mechanisms.
T. V. Ivanenko   +2 more
doaj   +1 more source

Majorana neutrino masses from neutrinoless double-beta decays and lepton-number-violating meson decays

open access: yesPhysics Letters B, 2016
The Schechter–Valle theorem states that a positive observation of neutrinoless double-beta (0νββ) decays implies a finite Majorana mass term for neutrinos when any unlikely fine-tuning or cancellation is absent.
Jun-Hao Liu, Jue Zhang, Shun Zhou
doaj   +1 more source

Can the Theory of Motivation Explain Migration Decisions? [PDF]

open access: yes
According to Abraham Maslow's motivational theory, human action is motivated by five groups of human needs. The model introduced in this paper exploits Maslow's theory to explain migration flows between regions.
Natálie Reichlová
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

An assay for beta-adrenergic receptors in isolated human fat cells.

open access: yesJournal of Lipid Research, 1982
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt   +3 more
doaj   +1 more source

A method for data base management and analysis for wind tunnel data [PDF]

open access: yes
To respond to the need for improved data base management and analysis capabilities for wind-tunnel data at the Langley 16-Foot Transonic Tunnel, research was conducted into current methods of managing wind-tunnel data and a method was developed as a ...
Biser, Aileen O.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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