Results 61 to 70 of about 1,352,947 (309)

Neutrinoless double beta decay in chiral effective field theory: lepton number violation at dimension seven

open access: yesJournal of High Energy Physics, 2017
We analyze neutrinoless double beta decay (0νββ) within the framework of the Standard Model Effective Field Theory. Apart from the dimension-five Weinberg operator, the first contributions appear at dimension seven.
V. Cirigliano   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Comparison Effect of Prescription Drugs on the Occurrence and the Number of Attacks in Patients with Multiple Sclerosis

open access: yesمجله دانشکده پزشکی اصفهان, 2018
Background: Treatment has a major effect on attacks in patients with multiple sclerosis (MS). This study aimed to determine the effect of the type of used drug on occurrence and number of attacks in patients with multiple sclerosis.
Marjan Jamalian   +4 more
doaj   +1 more source

Investigating the role of islet cytoarchitecture in its oscillation using a new beta-cell cluster model. [PDF]

open access: yesPLoS ONE, 2007
The oscillatory insulin release is fundamental to normal glycemic control. The basis of the oscillation is the intercellular coupling and bursting synchronization of beta cells in each islet.
Aparna Nittala   +2 more
doaj   +1 more source

Synthesis of RNA Nucleotides under Probably Prebiotic Conditions [PDF]

open access: yes, 2022
RNA being composed of multiple covalently linked nucleotides is thought to have been a precursor to life circa 4.3-3.8 billion years ago. Non-enzymatically formed adenosine monophosphate (AMP), more specifically, is a vitally important subtopic of the ...
Stimson, Ryan
core   +1 more source

Reduced number of endothelial progenitor cells in adult patients with beta thalassemia major

open access: yesAnnals of Hematology
Beta-thalassemia major (TM) is associated with a high incidence of thromboembolic events and prothrombotic changes, suggesting a chronic hypercoagulable state.
Idan Goldberg   +9 more
doaj   +1 more source

Estimating discrete curvatures in terms of beta numbers

open access: yes, 2016
For an arbitrary Radon measure $μ$ we estimate the integrated discrete curvature of $μ$ in terms of its centred variant of Jones' beta numbers. We farther relate integrals of centred and non-centred beta numbers. As a corollary, employing the recent result of Tolsa [Calc. Var.
openaire   +3 more sources

Local set approximation: Mattila-Vuorinen type sets, Reifenberg type sets, and tangent sets [PDF]

open access: yes, 2014
We investigate the interplay between the local and asymptotic geometry of a set $A \subseteq \mathbb{R}^n$ and the geometry of model sets $\mathcal{S} \subset \mathcal{P}(\mathbb{R}^n)$, which approximate $A$ locally uniformly on small scales.
Badger, Matthew, Lewis, Stephen
core   +1 more source

The beta-transformation's companion map for Pisot or Salem numbers and their periodic orbits [PDF]

open access: yes, 2017
The -transformation of the unit interval is de ned by T (x) := x (mod 1). Its eventually periodic points are a subset of [0; 1] intersected with the eld extension Q( ). If > 1 is an algebraic integer of degree d > 1, then Q( ) is a Q-vector space
Maia, Bruno
core   +1 more source

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