Results 41 to 50 of about 10,727,813 (262)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The rate of transient beta frequency events predicts behavior across tasks and species
eLife, 2017 Beta oscillations (15-29Hz) are among the most prominent signatures of brain activity. Beta power is predictive of healthy and abnormal behaviors, including perception, attention and motor action.
Hyeyoung Shin +4 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
La danza, a cura di Simone Beta. Traduzione di Marina Nordera, con testo a fronte
, 1992 Il volume consiste nella traduzione italiana (per opera di Marina Nordera) del trattato La danza (De saltatione) di Luciano. L'introduzione (pp. 9-47), le note al testo (pp. 111-138) e la bibliografia (pp. 139-142) sono di Simone Beta.
BETA, SIMONE, Nordera M.
core +1 more source
The Scientific World JournalWe study the variation in plasma beta, Alfven Mach number, and magnetosonic Mach number during different geomagnetic storms of solar cycles 23, 24, and 25.
Ashutosh Giri +4 more
doaj +1 more source
Reproductive Biology and Endocrinology, 2005 Background TGF beta and its receptors are present in both germ cells and somatic cells of the male gonad. However, knock-out strategies for studying spermatogenesis regulation by TGF beta have been disappointing since TGF beta-or TGF beta receptor-null ...
Sabido Odile +4 more
doaj +1 more source
Frontiers in Endocrinology, 2023 BackgroundUp to now, the physiology, pathology, and recovery of beta-cells have been intensively studied and made great progress, and these are of major significance for the treatment of related diseases.
Yunpeng Luo +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The place of metoprolol tartrate in the treatment of cardiovascular diseases
Медицинский совет, 2016 Since the beginning of the 1960s, beta-blockers have been number one medications in the treatment of cardiovascular diseases. A number of randomized controlled trials (RCTs) demonstrated positive effect of beta-blockers on morbidity and mortality [1]. It
N. V. Romanova, I. V. Zhirov
doaj +1 more source