Results 21 to 30 of about 1,376,916 (232)

THE EFFECT OF SOURSOP LEAF EXTRACT ON PANCREATIC BETA CELL COUNT AND FASTING BLOOD GLUCOSE IN MALE WISTAR RATS EXPOSED TO A HIGH-FAT DIET AND STREPTOZOTOCIN

open access: yesFolia Medica Indonesiana, 2017
Based on some researches known that soursop leaf extract can improve beta cell injury. The aims of this study was to analyze the effect of soursop leaf extract on fasting blood glucose (FBG) and pancreatic beta cell number in male Wistar rats wich were ...
Dewa Ayu Agung Alit Suka Astini   +4 more
doaj   +1 more source

Exendin-4 Promotes Beta Cell Proliferation via PI3k/Akt Signalling Pathway

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: Prevention of diabetes requires maintenance of a functional beta-cell mass, the postnatal growth of which depends on beta cell proliferation.
Chaoxun Wang   +5 more
doaj   +1 more source

Tangent points of lower content d‐regular sets and β numbers [PDF]

open access: yesJournal of the London Mathematical Society, 2019
Given a lower content $d$-regular set in $\mathbb{R}^n$, we prove that the subset of points in $E$ where a certain Dini-type condition on the so-called Jones $β$ numbers holds coincides with the set of tangent points of $E$, up to a set of $\mathcal{H}^d$-measure zero.
openaire   +2 more sources

Descent c-Wilf Equivalence [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2017
Let $S_n$ denote the symmetric group. For any $\sigma \in S_n$, we let $\mathrm{des}(\sigma)$ denote the number of descents of $\sigma$, $\mathrm{inv}(\sigma)$ denote the number of inversions of $\sigma$, and $\mathrm{LRmin}(\sigma)$ denote the number of
Quang T. Bach, Jeffrey B. Remmel
doaj   +1 more source

Pax4 Expression does not Transduce Pancreatic Alpha Cells to Beta Cells

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: The lack of available beta cells greatly limits the use of beta cell transplantation as a therapy for diabetes. Thus, generation of beta cells from other sources is substantially required.
Ling Chen   +5 more
doaj   +1 more source

Accessible surfaces of beta proteins increase with increasing protein molecular mass more rapidly than those of other proteins. [PDF]

open access: yesPLoS ONE, 2011
Here we present a systematic analysis of accessible surface areas and hydrogen bonds of 2554 globular proteins from four structural classes (all-α, all-β, α/β and α+β proteins) that is aimed to learn in which structural class the accessible surface area ...
Anna V Glyakina   +2 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

MS treatment optimization: factors associated with poor clinical response in Nab positive patients [PDF]

open access: yesRomanian Journal of Neurology, 2016
Background and purpose. Interferon beta (IFN beta) belongs to the first line of disease modifying therapy drugs in the treatment of relapsing-remitting multiple sclerosis being widely used in the chronic treatment of this pathology. The serum presence of
Amalia Cornea   +3 more
doaj   +1 more source

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