Results 231 to 240 of about 1,317,896 (291)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

On periodic $\beta$-expansions of Pisot numbers and Rauzy fractals (Analytic Number Theory and Related Topics)

, 2000
友紀 佐野, 俊次 伊藤
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Analysis of Short-Term Subjective Well-Being/Comfort and Its Correlation to Different EEG Metrics. [PDF]

Sensors (Basel)
Wutzl B, Leibnitz K, Ohsita Y, Murata M.
europepmc   +1 more source

Copy Number Variation of the Beta-Defensin Genes in Europeans: No Supporting Evidence for Association with Lung Function, Chronic Obstructive Pulmonary Disease or Asthma

, 2014
Louise V. Wain, Linda Odenthal-Hesse, Razan Abujaber, Ian Sayers, Caroline Beardsmore, Erol Gaillard, Sally Chappell, Cristian Dogaru, Tricia M. McKeever, Tamar Guetta‐Baranes, Noor Kalsheker, Claudia E. Kuehni, Ian P. Hall, Martin D. Tobin, Edward J. Hollox   +14 more
openalex   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study. [PDF]

PLoS Comput Biol
Karagiannis TT, Chen Y, Bald S, Tai A, Reed ER, Milman S, Andersen SL, Perls TT, Segrè D, Sebastiani P, Short MI.   +10 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dynamic evolution of intracortical and corticomuscular connectivity during reach-and-grasp movement planning and execution. [PDF]

Sci Rep
Sanchez-Bautista JA, Antelis JM, Mendoza-Montoya O.   +2 more
europepmc   +1 more source

The number of receptors for beta-melanocyte stimulating hormone in Cloudman melanoma cells is increased by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin.

, 1977
A. Dipasquale, Joseph McGuire, János Varga   +2 more
openalex   +2 more sources