Results 111 to 120 of about 53,686 (285)

Deteksi Mutasi Langka, Delesi 619 Bp, Pada Gen Beta-Globin Dari Etnis Melayu Mahasiswa Fakultas Kedokteran Universitas YARSI [PDF]

, 2015
Beta-thalassemia merupakan gangguan hematologis autosomal yang secara genetis mengakibatkan berkurangnya sintesis beta-globin di hemoglobin. Beta-talasemia sebagian besar disebabkan oleh mutasi titik, insersi atau delesi dalam gen beta-globin yang ...
Kenconoviyati, K. (Kenconoviyati), Prayuni, K. (Kinasih), Sofro, A. S. (Abdul), Susilowati, R. (RW), Yuliwulandari, R. (Rika)   +4 more
core  

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

Aging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan, Simon Reinhard, Anna Picca, Emanuele Marzetti, Christiaan Leeuwenburgh, James F. Collins, Stephen D. Anton   +6 more
wiley   +1 more source

The levels of nitric oxide in beta-thalassemia minor

Turkish Journal of Hematology, 2008
OBJECTIVE: The aim of this study was to investigate the relationship between NO (nitric oxide) and beta-thalassemia minor. METHODS: A total of 60 patients with beta-thalassemia minor (30 M, 30 F) were included in the study. The control group consisted of
Yalçın Başaran, İsmet Aydoğdu, Mehmet Ali Erkurt, Nihayet Bayraktar   +3 more
doaj  

Beta Thalassemia Major with Diabetes Mellitus: A Case Report

, 2021
Sneha Mhaske, Abhijit Shinde, Sonal Shinde, Ramesh K. Kothari, Ganesh Misal, Sushruta Kumar, Prof. Dr. Sunil Natha Mhaske   +6 more
openalex   +2 more sources

Validity of naked eye single tube red cell osmotic fragility test (NESTROFT) in screening of beta-thalassemia trait [PDF]

, 2011
زمینه و هدف: تالاسمی متداولترین اختلال تک ژنی است که رهایی از آن از طریق درمان قطعی ممکن نبوده و مستلزم پیشگیری از طریق به کارگیری یک روش قابل اعتماد و کم هزینه برای غربالگری ناقلین و در مرحله بعد ارایه آموزش، مشاوره ژنتیک، تشخیص قبل از تولد و خاتمه ...
Amini, S.A., Amini-NajafAbadi, H., Gholami, A., Nikoukar, M.   +3 more
core  

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

Advanced Science, Volume 13, Issue 5, 27 January 2026.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li, Yaxin Zhu, Yumeng Yan, Jifeng Wang, Lili Niu, Xiang Ding, Mengmeng Zhang, Zhensheng Xie, Tanxi Cai, Xiaojing Guo, Jianming Luo, Peng An, Xiangqian Guo, Fuquan Yang   +13 more
wiley   +1 more source

Association between genotype and disease complications in Egyptian patients with beta thalassemia: A Cross-sectional study [PDF]

, 2018
Tamer Hassan, Marwa Zakaria, Manar Fathy, Mohamed Arafa, Sherif El Gebaly, Ahmed A. Emam, Attia Abdel Wahab, Mohamed M. Shehab, Hosam Salah, Mai M. Malek, Khaled El Gerby   +10 more
openalex   +1 more source

Insulin-like growth factor-1 levels in children with Beta-thalassemia minor [PDF]

, 2008
Objective: Growth retardation in children with b-thalassemia major is multifactorial. Some etiologies described for this condition are hemochromatosis, disturbed growth hormone (GH) / insulin growth factor-1 (IGF-1) axis, undernutrition and ...
Hamdollah Karamifar, Mehran Karimi, Nargrs Sobhani   +2 more
core  

Unstable Hemoglobin, a Rare but Significant Cause of Hemolytic Anemia: Recognition of Peripheral Smear Findings Is Crucial for Diagnosis

International Journal of Laboratory Hematology, EarlyView.
Ryan C. Shean, Archana Agarwal, Anton V. Rets   +2 more
wiley   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

ChemBioChem, Volume 27, Issue 1, January 2026.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source