Results 11 to 20 of about 30,419 (262)
Journal of Pathology of Nepal, 2014 Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or more of the globin chains. About 1.5% of the global population (80 to 90 million people) are carriers of beta Thalassemia. More than 200 mutations are described in beta thalassemia. However not all mutations are common in different ethnic groups.
R. C. Jha, S Jha
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Correlation of Oxidative Stress with Serum Trace Element Levels and Antioxidant Enzyme Status in Beta Thalassemia Major Patients: A Review of the Literature [PDF]
Anemia, 2012 Beta thalassemia major is an inherited disease resulting from reduction or total lack of beta globin chains. Patients with this disease need repeated blood transfusion for survival.
Mohammad, Z. H. +3 more
core +4 more sources
The history of beta-thalassemia in Turkey.
The Turkish journal of pediatrics, 1991 The first two patients with beta-thalassemia major in Turkey, were reported in 1941. However, the importance of beta-thalassemia as a health problem was brought to the attention of physicians only after 1950. In Turkey, the clinical and hematological pictures of beta thalassemia were found to be mostly heterogenous.
M Aksoy
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Pre-Natal Diagnosis of beta – Thalassemia by Chorionic Villous Sampling [PDF]
Journal of Rawalpindi Medical College, 2009 Background: To promote the utility of Chorionic Villous Sampling (CVS) for pre-natal diagnosis of beta thalassemia in at risk population and to highlight its demographic area distribution and effect of consanguinity.
Shazia Syed, Faiza Shafi, Lubna Yasmeen, Humera Noreen and Rizwana Chaudhry
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Venous thromboembolism risk assessment among beta-thalassemia patients
Journal of Applied Hematology, 2023 BACKGROUND: Thromboembolic (TE) disorders are among the most common complications of beta-thalassemia. We designed this cross-sectional study to investigate the state of hypercoagulability and platelet activation in patients with beta-thalassemia ...
Hasnaa A Abo-Elwafa +5 more
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eJHaem, 2021 The genotype and phenotype correlation between coinheritance of heterozygous beta‐thalassemia with the alpha‐globin triplication is unclear. In this study we have investigated and reviewed alpha triplication frequency in beta‐thalassemia carriers, sickle
Mohammad Hamid +6 more
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Studies on molecular spectrum of beta thalassemia among residents of Chennai
AIMS Molecular Science, 2022 Beta thalassemia is caused by a mutation in the human beta globin gene. More than 400 causative mutations have been characterized in the Hemoglobin Subunit Beta (HBB) gene.
Bhuvana Selvaraj +4 more
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The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran [PDF]
Epidemiology and Health, 2018 OBJECTIVES Thalassemia is a common genetic disease in Iran, especially in the north and south of Iran. The present study sought to determine the survival rate of patients with thalassemia in highly endemic regions of Iran and its variation in patients ...
Alireza Ansari-Moghaddam +4 more
doaj +1 more source
Trends in Pediatrics, 2021 Defects in protein structure or synthesis of hemoglobin are called hemoglobinopathies. Thalassemia is the most common hemoglobinopathy, and it is estimated that 5% of the world population carries at least one variant allele of thalassemia.
Tekin Aksu, Sule Unal
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Comparison of biochemical parameters of prevalent hemoglobinopathies with healthy individuals
Medicine Science, 2020 Thalassemia is the most frequently seen monogenetic disorders around the world that is inherited as a recessive single-gene disease, resulting from mutations in α-or β-globin gene clusters.
Emrah Yerlikaya +2 more
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