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Ophthalmic Evaluation in Beta-Thalassemia
The Indian Journal of Pediatrics, 2017To determine the association of ocular manifestations in beta-thalassemia with the patient's age, blood transfusion requirements, average serum ferritin and dose and duration of iron chelation therapy.Sixty multi-transfused beta thalassemia patients of 12 to 18 y of age on chelation therapy were included in this cross-sectional analysis. Structural and
Rashid H, Merchant +3 more
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[Beta-Thalassemia in Poland. I. Mediterranean mutations in beta-thalassemia].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006The aim of the present investigation was to verify a common view that thalassemia in Poland is a very rare disease.600 patients (270 male and 330 female) aged 2-85 years with microcytosis and no evidence of iron deficiency were examined for beta-thalassemia. Hemoglobin A2 and hemoglobin F and bilirubin were evaluated.
Ewa, Zdebska +8 more
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Beta-Thalassemia Syndromes and Pregnancy
Obstetrical & Gynecological Survey, 1994The literature relating to homozygous beta-thalassemia and the problems these patients have during their pregnancy is reviewed and another case report of a twin pregnancy in a homozygous beta-thalassemia individual is included. The majority of cases described refer to the intermedia clinical form of the hematological problem because patients with ...
C, Savona-Ventura, F, Bonello
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The Silent Carrier of Beta Thalassemia
New England Journal of Medicine, 1969Abstract A family of Albanian descent had an unusual form of beta thalassemia. The father of two children with mild thalassemia major had normal red-cell morphology and normal levels of hemoglobins A2 and F, whereas the mother had elevated hemoglobin A2.
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Platyspondyly in treated beta-thalassemia
European Journal of Radiology, 1994Flattening of the vertebral bodies with a platyspondyly appearance is described in 14 patients selected for evaluation of short stature from 106 patients affected by thalassemia major, who received an intensive transfusion regimen combined with continuous chelation therapy.
C, Orzincolo +2 more
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Cardiac involvement in beta-thalassemia major and beta-thalassemia intermedia.
Hemoglobin, 2005The forms and severity of cardiac complications were investigated in patients with asymptomatic thalassemia intermedia and thalassemia major by M-mode, bi-dimensional echocardiography (ECHO) and echo-Doppler. Twenty-eight patients of both sexes with beta-thalassemia intermedia (beta-TI), mean age 23.2 +/- 6.3 years, untransfused or minimally transfused,
Mara, Ferrara +7 more
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[Beta-thalassemia in Germany. Results of cooperative beta-thalassemia study].
Klinische Padiatrie, 2000At present, about 300 patients with thalassemia major are living in Germany. Starting in 1991, a multicenter study in Germany has concentrated on identifying all patients suffering from thalassemia as well as on establishing a uniform therapy protocol including follow-up diagnostic procedures.
H, Cario, K, Stahnke, E, Kohne
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In Brief: Casgevy for Beta Thalassemia
The Medical Letter on Drugs and TherapeuticsExagamglogene autotemcel (Casgevy – Vertex), a cell-based gene therapy recently approved for treatment of sickle cell disease1, has now been approved by the FDA for treatment of patients ≥12 years old with transfusion-dependent beta thalassemia.
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