Results 51 to 60 of about 30,419 (262)

In Patients with Minor Beta-Thalassemia, Cognitive Performance Is Related to Length of Education, But not to Minor Beta-Thalassemia or Hemoglobin Levels [PDF]

, 2019
Objective:; Thalassemia is one of the most frequent monogenic disorders, leading to impairment in the maturation and survival of red blood cells. The question examined here is whether, and if so, to what extent, people with beta-thalassemia might also be
Ahmadpanah, Mohammad, Asadi, Yasaman, Brand, Serge, Ghasemibasir, Hamidreza, Haghighi, Mohammad, Khanlarzadeh, Elham   +5 more
core  

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Prevalence of Co-Inheritance of Alpha-Thalassemia with Beta-Thalassemia and Beta-Hemoglobinopathy in Ahvaz City

Journal of Ardabil University of Medical Sciences, 2013
Background: Co-inheritance of hemoglobin gene defects is a rare important status that can lead to double heterozygote or homozygote with significant clinical manifestations. Such conditions can be observed in co-inheritance of alpha-thalassemia with beta-
Najmaddin Saki, Akbar Dorgalaleh, Zahra Kashani Khatib, Shaban Alizadeh, Fakher Rahim, Hamid Galehdari, Bijan Kaikhaei, Mohammad Pedram, Ali Dehghani Fard   +8 more
doaj  

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Genomic technologies and the diagnosis of 46, XY differences of sex development

Andrology, EarlyView.
Abstract Differences/disorders of sex development can be caused by disruptions to the molecular and cellular mechanisms that control development and sex determination of the reproductive organs with 1:100 live births affected. Multiple genes are associated with 46, XY differences/disorders of sex development that can cause varying clinical phenotypes ...
Firman Idris, Andrew H. Sinclair, Katie L. Ayers   +2 more
wiley   +1 more source

The shortcut strategy for beta thalassemia prevention

Hematology Reports, 2018
We propose antenatal blood tests using high-resolution DNA melting (HRM) analysis for beta thalassemia mutation detection after hemoglobin A2 estimation as a modified strategy for the identification of beta thalassemia at-risk couples.
Narutchala Suwannakhon, Khajohnsilp Pongsawatkul, Teerapat Seeratanachot, Khwanruedee Mahingsa, Arunee Pingyod, Wanwipa Bumrungpakdee, Torpong Sanguansermsri   +6 more
doaj   +1 more source

A Child Lost to Follow Up Carrying Beta Thalassemia Major: A Case Report

Journal of Nepal Medical Association, 2020
Thalassemia is inherited autosomal recessive disorders characterized by reduced rate of hemoglobin synthesis due to a defect in alpha or beta globin chain synthesis. Maldives has a beta thalassemia prevalence rate of 16–18%.
Prakash Banjade, Jeetendra Bhandari
doaj   +1 more source

Challenges of Blood Transfusions in β-Thalassemia during COVID-19 Pandemic in Low Middle-Income Country

Journal of Pharmaceutical Care, 2022
In China Hubei province, Wuhan was recognized as the focus of an epidemic of pneumonia of unidentified origin in December 2019. Ultimately, intense focus on the disease was raised worldwide and in China.
Kashif Ali, Kashif Rizvi, Saqib Hussain Ansari, Faisal Zahid   +3 more
doaj   +1 more source

HUBUNGAN ANTARA STRES DENGAN STRATEGI COPING PADA ORANG TUA YANG MEMILIKI ANAK PENDERITA TALASEMIA BETA MAYOR DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH [PDF]

, 2013
Background: Beta thalassemia major is a disorder characterized by defective hemoglobin production and excessive destruction of red blood cells. This life-threatening illnesses suffered by children can lead to parental stress and depression. How to cope
RINA SYAFRITA
core  

The Hospitalisation Experience and Distress Among Jewish and Bedouin Parents of Hospitalised Children in Israel

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study tested the relationship between the hospitalisation experience and distress among Jewish and Bedouin parents of hospitalised children in the south of Israel. Methods An anonymous self‐reported questionnaire containing the Distress Thermometer for Parents and the Parental Perceptions of Hospital Care in Children was completed by ...
Elena Gelman, Ayalet Noham, Ilana Livshiz‐Riven   +2 more
wiley   +1 more source