Results 71 to 80 of about 607,752 (259)

Pattern of red cell indices in beta thalassemia trait and E trait

Haematology Journal of Bangladesh
Background: Thalassemia is the most common single gene disorder that affects globin chain synthesis.  Hb electrophoresis is the gold standard for detection of beta thalassemia trait and E-trait, but it is costly and not available in upazila and district
Nahid Sultana
doaj   +1 more source

Evaluation of physical growth of Patient WithThalassemia Major Based on NCHS criteria [PDF]

Background: Beta thalassemia major, including the conditions in which the natural growth due to complications from those diseases can be disrupted. Despite the recent advances in treating these patients, growth retardation in a significant percentage of ...
آریش, گیتی, اللهیاری, ایراندخت, سیدجوادی, مهری, مظاهری, عفت, محمدی, راحله   +4 more
core  

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Association Between Thalassemia and Leucocytic DNA Damage: A Pilot Study

Journal of Basic and Applied Research in Biomedicine, 2022
Objectives: Thalassemia with frequent blood transfusion was considered under oxidative stress because of the chance of iron overload. Patients with thalassemia trait with no blood transfusion might also suffered from oxidative stress because of ...
Yim Szeto, Charlton CHAN
doaj   +2 more sources

In Patients with Minor Beta-Thalassemia, Cognitive Performance Is Related to Length of Education, But not to Minor Beta-Thalassemia or Hemoglobin Levels

Iranian Journal of Psychiatry, 2018
Objective: Thalassemia is one of the most frequent monogenic disorders, leading to impairment in the maturation and survival of red blood cells. The question examined here is whether, and if so, to what extent, people with beta-thalassemia might also be ...
Mohammad Ahmadpanah, Yasaman Asadi, Mohammad Haghighi, Hamidreza Ghasemibasir, Elham Khanlarzadeh, Serge Brand   +5 more
doaj  

Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia

, 2010
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Pier Luigi Cocco, Alessandra Spiga, Fabrizio Angius, Stefania Vacquer, Maria Eliana Lai, Antonella Mandas, Maria Paola Carta, Sandra Dessi   +7 more
core  

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Prevalence of Candida albicans in the oral cavity of Beta Thalassemia Major and Thalassemia Minor Patients [version 1; peer review: 2 approved]

F1000Research
Aims To examine the correlation between iron, ferritin concentrations, and C. albicans infection in individuals with beta-thalassemia major and beta-thalassemia minor compared with healthy subjects.
Maha Adel Mahmood, Saba Sami Abd Al Wahab   +1 more
doaj   +1 more source

L-carnitine in beta thalassemia

Indian Pediatrics, 2009
This study was conducted to determine L-carnitine levels in regularly transfused and chelated beta thalassemia patients (n=40; mean age, 17.5+/-5.0 years). Ten age matched controls were also studied. The mean L-carnitine level in thalassemic patients was 23.71+/- 7.3 microM as compared to control 29.26+/-2.37 microM ...
Rashid, Merchant, Abhay, Jain, Amish, Udani, Vipla, Puri, Mallika, Kotian   +4 more
openaire   +2 more sources

Effect of alpha-gene numbers on the expression of beta-thalassemia intermedia, beta-thalassemia and (delta beta)(0)-thalassemia traits

, 1998
The effects of variations in alpha-gene numbers on phenotypical expression of beta-thalassemia are assessed in 11 subjects of 8 families. The study indicates that coexistence of alpha-thalassemia (-alpha(3.7)/alpha alpha) decreases the HbF in IVSI-6 ...
Altay, C, Gurgey, A, Gumruk, FATMA, Oner, C, Oner, R, Mergen, HATİCE   +5 more
core   +1 more source