Results 131 to 140 of about 2,268,451 (316)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2003 La sezione del volume curata da Simone Beta comprende tre capitoli: 1) le feste: le grandi Dionisie, le Lenee, le Dionisie rurali, le Antesterie (pp. 39-48) 2) la struttura e le caratteristiche dei teatri greci; il teatro di Dioniso ad Atene (pp. 49-54)
BETA, SIMONE
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Tragici greci. Eschilo Sofocle Euripide
, 2007 Il volume contiene la traduzione di alcune tragedie di Eschilo (Agamennone, Eumenidi, Coefore), Sofocle (Antigone, Edipo re, Edipo a Colono) ed Euripide (Alcesti, Medea, Ippolito, Baccanti). A Simone Beta si devono l'introduzione (pp.
Beta, Simone, Eschilo, Sofocle, Euripide
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
APPLICATION OF BLUME METHOD IN FORECASTING RISK ON THE EXAMPLE OF PUBLIC COMPANIES LISTED ON WIG20
Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2016 The paper presents the results of studies on the use of Blume’s beta to identify systematic risk of companies listed on the Warsaw Stock Exchange. For this purpose, beta values for WIG20 companies for 2014-2016 were calculated.
Bartłomiej Lisicki
doaj
, 2001 il volume contiene la traduzione italiana (con testo latino originale a fronte) della commedia di Terenzio "La donna di Andro". A Simone Beta si devono l'introduzione (pp.
Beta, Simone, Publio Afro Terenzio
core
A Challenge to the Reader. The Twelve Byzantine Riddles of Pal. gr. 356
, 2016 This paper deals with the collection of twelve Byzantine riddles contained in Pal. gr. 356 (f. 168), a manuscript written between the thirteenth and the fourteenth century.
Simone Beta, Beta, Simone
core +1 more source