Results 81 to 90 of about 4,641,185 (396)

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Molecular Dynamics Study of Conformations of Beta-Cyclodextrin and its Eight Derivatives in Four Different Solvents [PDF]

open access: yes, 2017
Understanding the atomic level interactions and the resulting structural characteristics is required for developing beta-cyclodextrin ($\beta$CD) derivatives for pharmaceutical and other applications. The effect of four different solvents on the structures of the native $\beta$CD and its hydrophilic (methylated $\beta$CD; ME$\beta$CD and hydroxypropyl $
arxiv   +1 more source

BETA-BEAMS [PDF]

open access: yesParticle Physics on the Eve of LHC, 2006
8 pages, 1 table, 5 figures, Proceedings of "13th Lomonosov Conference on Elementary Particle Physics"
openaire   +8 more sources

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1999
beta-Catenin plays a dual role in the cell: one in linking the cytoplasmic side of cadherin-mediated cell-cell contacts to the actin cytoskeleton and an additional role in signaling that involves transactivation in complex with transcription factors of ...
M. Shtutman   +6 more
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

A Multiscale Pricing Model with the Wavelet Analysis Approach, Fama-French Three-Factor Model, and Nonliquidity in Tehran Stock Exchange [PDF]

open access: yesIranian Journal of Finance, 1999
The aim of this paper is to analyze the multiscale pricing model with the wavelet analysis approach, Fama-French three-factor model, and nonliquidity in Tehran Stock Exchange.
Mohammadreza Rostami   +2 more
doaj   +1 more source

UPAYA MENINGKATKAN PEMAHAMAN KONSEP SUMBER DAYA ALAM DALAM IPA MELALUI MODEL PEMBELAJARAN TEAMS GAMES TOURNAMENT (TGT) PADA SISWA KELAS IV SD (PENELITIAN TINDAKAN KELAS PADA SISWA SD NEGERI KALORAN 2 KECAMATAN GEMOLONG KABUPATEN SRAGEN TAHUN PELAJARAN 2011/2012) [PDF]

open access: yes, 2013
Beta Kurnianingrum, AN IMPROVE UNDERSTANDING OF THE CONCEPT OF NATURAL RESOURCES THROUGH LEARNING MODEL IPA TEAMS GAMES TOURNAMENT (TGT) ON THE FOURTH GRADE STUDENTS IN SD (CLASS ACTION RESEARCH ON
KURNIANINGRUM , BETA
core  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

RELIGIOUS THEME IN O’ HENRY’S SHORT STORIES: A SOCIOLOGICAL PERSPECTIVE [PDF]

open access: yes, 2011
PUTRI BETA CINTANTYA. A 320 070 305. RELIGIOUS THEME IN O’ HENRY’S SHORT STORIES: A SOCIOLOGICAL PERSPECTIVE. MUHAMMADIYAH UNIVERSITY OF SURAKARTA. RESEARCH PAPER. 2011. This study examines how religious theme is reflected in O’
Cintantya, Putri Beta
core  

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