Results 191 to 200 of about 153,861 (252)

Avidity of anti-beta-2-glycoprotein I antibodies

Autoimmunity Reviews, 2005
The terms affinity and avidity are often used indiscriminately, despite clearly differing. Since affinity refers to monovalent binding of antibodies to a monovalent epitope, the majority of data on the binding of anti-beta2-glycoprotein I antibodies (anti-beta2-GPI) characterized their avidity rather than affinity.
B, Bozic   +3 more
openaire   +2 more sources

Beta-2-glycoprotein I antibodies in patients with thrombosis

Scandinavian Journal of Clinical and Laboratory Investigation, 2003
The laboratory diagnosis of antiphospholipid antibody syndrome currently requires two consecutive positive results in either lupus anticoagulant or anticardiolipin antibody assays. Antibodies against beta-2-glycoprotein I (abeta2-GPI) are suggested as a new marker for the syndrome.
F, Ebeling   +4 more
openaire   +2 more sources

Beta-2-glycoprotein I Dependent Lupus Anticoagulants Form Stable Bivalent Antibody Beta-2-Glycoprotein I Complexes on Phospholipid Surfaces

Thrombosis and Haemostasis, 1998
SummaryThe precise mechanism by which Beta-2-glycoprotein I (β2GPI-) dependent lupus anticoagulants lengthen phospholipid-dependent clotting reactions is still poorly understood. In order to study this, murine monoclonal antibodies (moabs) against human β2GPI were raised. Eight of the 21 anti-β2GPI moabs, obtained from 2 fusions, fulfilled the criteria
J, Arnout   +4 more
openaire   +2 more sources

Beta 2 glycoprotein I-function in health and disease

Thrombosis Research, 2004
Beta-2 glycoprotein I (beta2GPI) is the principal target of autoantibodies in the antiphospholipid syndrome (APS). It is abundant in human plasma and shares high homology between different mammalian species. Although the exact physiological function of beta2GPI has not been fully elucidated, several interactions have been described with other proteins ...
Spiros, Miyakis   +2 more
openaire   +2 more sources

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