Results 211 to 220 of about 153,861 (252)
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Thrombosis and haemostasis, 1995
Lupus anticoagulants are a group of antibodies commonly found in patients with autoimmune diseases such as systemic lupus erythematosus. Lupus anticoagulants inhibit phospholipid dependent coagulation and may bind to negatively charged phospholipids.
I, Schousboe, M S, Rasmussen
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Lupus anticoagulants are a group of antibodies commonly found in patients with autoimmune diseases such as systemic lupus erythematosus. Lupus anticoagulants inhibit phospholipid dependent coagulation and may bind to negatively charged phospholipids.
I, Schousboe, M S, Rasmussen
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New Tests to Detect Antiphospholipid Antibodies: Anti-Domain I Beta-2-Glycoprotein-I Antibodies
Current Rheumatology Reports, 2014Beta-2 glycoprotein I (β2GPI) is the main antigenic target for antiphospholipid antibodies (aPL), the serological markers of antiphospholipid syndrome (APS). Domain I (DI) of β2GPI has lately been identified as the main epitope targeted by antibodies reacting against β2GPI. DI is a cryptic epitope, becoming available for autoantibody binding when β2GPI
C.B. Chighizola, M. Gerosa, P.L. Meroni
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Thrombosis and haemostasis, 2003
To clarify the role(s) of anti-beta(2) GPI antibodies on thrombosis in anti-phospholipid antibody syndromes (APS), the effect of IgG from three patients on activated protein C (APC) was investigated using phospholipid vesicles and purified proteins. Two of the total IgG inhibited APC activity in the presence of beta(2)GPI, whereas the third IgG did not.
Tomonori, Izumi +4 more
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To clarify the role(s) of anti-beta(2) GPI antibodies on thrombosis in anti-phospholipid antibody syndromes (APS), the effect of IgG from three patients on activated protein C (APC) was investigated using phospholipid vesicles and purified proteins. Two of the total IgG inhibited APC activity in the presence of beta(2)GPI, whereas the third IgG did not.
Tomonori, Izumi +4 more
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Clinical significance of anti-beta 2-glycoprotein I antibodies.
Annales de medecine interne, 1997Antiphospholipid antibodies are a heterogeneous group of autoantibodies with clinical importance because of their strong association with thrombotic events. Recent evidence have shown that antiphospholipid antibodies are not directed against phospholipids, as has previously been thought, but are a part of a large family of autoantibodies against ...
O, Amengual +3 more
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Apolipoprotein H (beta-2-glycoprotein I) polymorphism in Asians.
Human biology, 1992Apolipoprotein H (APOH) (beta-2-glycoprotein I) polymorphism has been studied in 1159 Asians. The sample included 872 Chinese, 179 Asiatic Indians (Dravidian), 91 Filipinos, and 17 Malays. APOH polymorphism was determined by isoelectric focusing of sera in thin-layer polyacrylamide gels containing 3 M urea followed by immunoblotting. The frequencies of
Saha, N. +4 more
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Antibodies to beta(2)-glycoprotein I in ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland), 2000Antibodies to beta(2)-glycoprotein (beta(2)-GPI) have been associated with recurrent thrombotic events in patients with systemic lupus erythematosus. The present study investigated the prevalence of antibodies to beta(2)-GPI in an unselected group of patients with ischemic stroke.
Fiallo P +3 more
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[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2000
Apoptosis (programmed cell death) is accompanied by loss of phospholipid asymmetry, i.e., translocation of aminophospholipids such as phosphatidylserine to the outer leaflet of the plasma membranes, which results in recognition of these cells by macrophages.
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Apoptosis (programmed cell death) is accompanied by loss of phospholipid asymmetry, i.e., translocation of aminophospholipids such as phosphatidylserine to the outer leaflet of the plasma membranes, which results in recognition of these cells by macrophages.
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British journal of haematology, 1995
Some researchers claim that lupus anticoagulant-positive plasma may cause a false-positive reaction in the test for activated protein C (APC) resistance, a hereditary thrombophilic state characterized by abnormal factor V, which frequently causes venous thrombosis.
J, Matsuda +5 more
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Some researchers claim that lupus anticoagulant-positive plasma may cause a false-positive reaction in the test for activated protein C (APC) resistance, a hereditary thrombophilic state characterized by abnormal factor V, which frequently causes venous thrombosis.
J, Matsuda +5 more
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Thrombosis and haemostasis, 1995
beta 2 glycoprotein-I (beta 2GPI), a cofactor for antiphospholipid antibody (aPA) binding, binds to many anionic macromolecules including heparin. The nature of this interaction with heparin is not well understood and its effect on the purported biological functions of beta 2GPI is unknown.
T, McNally +4 more
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beta 2 glycoprotein-I (beta 2GPI), a cofactor for antiphospholipid antibody (aPA) binding, binds to many anionic macromolecules including heparin. The nature of this interaction with heparin is not well understood and its effect on the purported biological functions of beta 2GPI is unknown.
T, McNally +4 more
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