Results 221 to 230 of about 206,426 (300)

Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization. [PDF]

J Cancer
Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I.   +4 more
europepmc   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Genetic associations of plasma proteomics with dementia subtypes and neuroimaging markers. [PDF]

Alzheimers Dement (Amst)
Salih AM, Salatzki J, Wang Y, Akilu T, Maldonado C, Husain M, Neubauer S, Topiwala A, Altmann A, Raisi-Estabragh Z.   +9 more
europepmc   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

A Randomized, Placebo‐Controlled Trial of Hydroxychloroquine in Incomplete Lupus

Arthritis &Rheumatology, EarlyView.
Objective Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus erythematosus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity, and incidence of SLE.
Nancy J. Olsen, Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, David R. Karp   +14 more
wiley   +1 more source

Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach. [PDF]

Sci Rep
Pokorná J, Hadzima M, Křenková A, Smith JD, Šubr V, Kryštůfek R, Hubálek M, Starková J, Šrámková K, Etrych T, Kostka L, Sedlák F, Konvalinka J, Šácha P.   +13 more
europepmc   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, Accepted Article.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, The LN classification steering committee   +11 more
wiley   +1 more source

Computational screening and molecular modeling of probiotic-derived peptides targeting the conserved HR1 domain of SARS-CoV-2 spike protein. [PDF]

Sci Rep
Sattar A, Jahromi BS, Ghahi FSJ, Hoseini GNG, Fard NA.   +4 more
europepmc   +1 more source

Correlation between protein abundances and R_5-20 z-score among cases at baseline. Protein abundances, normalized to mean 0 and variance 1, are displayed on the y-axis. (TF, Serotransferrin; F2, Prothrombin; CFI, Complement factor I; HPX, Hemopexin; C4A/C4B, Complement C4b; GC, Vitamin D-binding protein; SERPINA7, Thyroxine-binding globulin; CFB, Complement factor B; APOH, Beta-2-glycoprotein 1; NTM, Neurotrimin).

Spela Kokelj (8356644), Per Larsson (386943), Emilia Viklund (11027586), Hatice Koca (15302098), Hanna Slogén (22008498), Lowie Vanfleteren (5913479), Bo Nilsson (54824), Karin Fromell (8639394), Johan Westin (321583), Anna-Carin Olin (168124)   +9 more
openalex   +1 more source

Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, Accepted Article.
Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source