Results 31 to 40 of about 88,568 (304)
Meat and Muscle Biology, 2021 The objective was to determine whether recombinant bovine somatotropin (rbST) enhanced live performance,skeletal muscle biological activity, and beta-adrenergic receptor expression of feedlot heifers during the finishing phase.
Alex Thompson +8 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundLeft ventricular (LV) remodeling consists in maladaptive changes in cardiac geometry and function following an insult such as ST-segment elevation myocardial infarction (STEMI).
Oriol Iborra-Egea +15 more
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Frontiers in Physiology, 2021 Brown and beige adipocytes are specialized to dissipate energy as heat. Sgk2, encoding a serine/threonine kinase, has been identified as a brown and beige adipocyte-specific gene in rodents and humans; however, its function in brown/beige adipocytes ...
Chul-Hong Park +5 more
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Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1993 The beta and gamma subunits of heterotrimeric guanine nucleotide-binding proteins (G proteins) have recently been shown to play an active role in signal transduction.
Sabine Müller +2 more
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A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach
Biomolecules, 2021 Obesity is a low-grade systemic inflammatory disease involving adipocytokines. As though Anmyungambi decoction (AMGB) showed significant improvement on obesity in a clinical trial, the molecular mechanism of AMGB in obesity remains unknown. Therefore, we
Dongyeop Jang +3 more
doaj +1 more source
Involvement of the Catecholamine Pathway in Glioblastoma Development
Cells, 2021 Glioblastoma (GBM) is the most aggressive tumor of the central nervous system (CNS). The standard of care improves the overall survival of patients only by a few months. Explorations of new therapeutic targets related to molecular properties of the tumor
Zoltán Kraboth +5 more
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Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations, which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) is an essential regulator for many G protein‐coupled receptors and subsequent
Xuejing Sun +9 more
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Breast Cancer: Basic and Clinical Research, 2008 Previous data from our laboratory have indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in breast cancer cell lines and that these pathways ...
Michael W. Hance +2 more
doaj +2 more sources
Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins. [PDF]
PLoS ONE, 2012 The complement of fungal cell surface proteins is widely regulated by ubiquitination of membrane proteins, which results in their endocytosis and vacuolar degradation.
Fortune F Shea +4 more
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The β-Adrenergic Receptor Kinase (GRK2) Is Regulated by Phospholipids [PDF]
Journal of Biological Chemistry, 1995 The beta-adrenergic receptor kinase (beta ARK) is a member of growing family of G protein coupled receptor kinases (GRKs). beta ARK and other members of the GRK family play a role in the mechanism of agonist-specific desensitization by virtue of their ability to phosphorylate G protein-coupled receptors in an agonist-dependent manner.
Yu Liu +4 more
openaire +3 more sources