Results 21 to 30 of about 2,306,523 (240)

The octopamine receptor Octβ2R regulates ovulation in Drosophila melanogaster.

open access: yesPLoS ONE, 2014
Oviposition is induced upon mating in most insects. Ovulation is a primary step in oviposition, representing an important target to control insect pests and vectors, but limited information is available on the underlying mechanism.
Junghwa Lim   +6 more
doaj   +1 more source

Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling

open access: yesBreast Cancer Research, 2022
Background Opioid and beta-adrenergic receptors are recently shown to cross talk via formation of receptor heterodimers to control the growth and proliferation of breast cancer cells.
Bénédicte Rousseau   +3 more
doaj   +1 more source

Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits

open access: yesAntioxidants, 2021
Recent studies have shown that carbonyl stress is a causative factor of schizophrenia, categorized as carbonyl stress-related schizophrenia (CS-SCZ).
Shin Koike   +8 more
doaj   +1 more source

Cardiac adrenergic control and atrial fibrillation [PDF]

open access: yes, 2010
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it causes substantial mortality. The autonomic nervous system, and particularly the adrenergic/cholinergic balance, has a profound influence on the occurrence of AF ...
Workman, A.J.
core   +1 more source

Beta 2-adrenergic pathway combats Alzheimer’s disease: Restoring cognition and synaptic integrity

open access: yesNeural Regeneration Research
Alzheimer’s disease is typified by amyloid-beta oligomer-mediated synaptic disruption, neuroinflammation, and mitochondrial loss of function, culminating in cognitive decline.
Shaomin Li, Shan-Xue Jin
doaj   +1 more source

In Silico Multitarget Profiling of Non-Selective Beta-Blockers Highlights Their Potential as Key Agents in Breast Cancer Adjuvant Therapy via ADRB2, ERBB2, and NPYR Receptors

open access: yesCurrent Issues in Molecular Biology
Breast cancer (BC) is associated with multiple molecular factors such as overexpression of the beta-2 adrenergic receptor (ADRB2) and the overproduction of its agonists (norepinephrine and epinephrine).
Felipe Muñoz-González   +3 more
doaj   +1 more source

Stevioside modulates oxidative damage in the liver and kidney of high fat/low streptozocin diabetic rats

open access: yesHeliyon, 2018
This study investigated the potential of stevioside to prevent oxidative DNA damage in the liver and kidney of type 2 diabetes mellitus (T2DM) using high fat-low streptozocin rat model. Rats were treated daily with 12.5, 25 and 50 mg/kg stevioside orally
Solomon Oladapo Rotimi   +5 more
doaj   +1 more source

Pharmaceuticals in the aquatic environment: β-blockers as a case study [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/09/2008.The presence of many human pharmaceuticals in the aquatic environment is now a worldwide concern and yet little is known of the chronic effects ...
Giltrow, Emma
core   +7 more sources

Prognostic Impact of Concomitant Beta-Blocker Use on Survival in EGFR-Mutant Metastatic Non-Small Cell Lung Cancer Patients Treated with Erlotinib

open access: yesMedicina
Background and Objectives: Erlotinib, a tyrosine kinase inhibitor (TKI), is an established therapy for patients with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations.
Oğuzhan Yıldız   +9 more
doaj   +1 more source

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

open access: yesMolecular Metabolism, 2018
Objective: The inappropriate release of free fatty acids from obese adipose tissue stores has detrimental effects on metabolism, but key molecular mechanisms controlling FFA release from adipocytes remain undefined.
Shangyu Hong   +16 more
doaj   +1 more source

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