Results 31 to 40 of about 26,478 (271)
Cardiac adrenergic control and atrial fibrillation [PDF]
, 2010 Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it causes substantial mortality. The autonomic nervous system, and particularly the adrenergic/cholinergic balance, has a profound influence on the occurrence of AF ...
Workman, A.J.
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Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. [PDF]
PLoS ONE, 2014 Spontaneous calcium waves in cardiac myocytes are caused by diastolic sarcoplasmic reticulum release (SR Ca(2+) leak) through ryanodine receptors.
Jerry Curran +13 more
doaj +1 more source
Glycyrrhetic acid synergistically enhances β₂-adrenergic receptor-Gs signaling by changing the location of Gαs in lipid rafts. [PDF]
PLoS ONE, 2012 Glycyrrhetic acid (GA) exerts synergistic anti-asthmatic effects via a β₂-adrenergic receptor (β₂AR)-mediated pathway. Cholesterol is an important component of the structure and function of lipid rafts, which play critical roles in the β₂AR-Gs-adenylate ...
Qian Shi +7 more
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Inhibition of the beta-adrenergic receptor kinase by polyanions.
The Journal of biological chemistry, 1989 The beta-adrenergic receptor kinase, which specifically phosphorylates the agonist-occupied beta-adrenergic receptor, is strongly inhibited by polyanions. Heparin and dextran sulfate inhibit the enzyme with an IC50 of approximately 0.15 microM. De-N-sulfated heparin is approximately 8-fold less potent.
J L, Benovic +3 more
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Phosphorylation and Activation of β-Adrenergic Receptor Kinase by Protein Kinase C [PDF]
Journal of Biological Chemistry, 1995 The aim of this study was to test the possible modification of beta-adrenergic receptor kinase (beta ARK) activity by second messengers and/or their downstream components. Using human mononuclear leukocytes (MNL), we found that calcium ionophores could elevate beta ARK activity by about 80% in a protein kinase C (PKC)-dependent manner.
Chuang TT +2 more
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Кубанский научный медицинский вестник, 2018 Heart failure is associated with profound sympathetic overactivation, which initially develops as an adaptive effect that supports cardiac contractile function.
O. E. OSADCHII
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Antioxidants, 2021 Recent studies have shown that carbonyl stress is a causative factor of schizophrenia, categorized as carbonyl stress-related schizophrenia (CS-SCZ).
Shin Koike +8 more
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Purification and characterization of the beta-adrenergic receptor kinase.
Journal of Biological Chemistry, 1987 The beta-adrenergic receptor kinase (beta-ARK) is a recently discovered enzyme which specifically phosphorylates the agonist-occupied form of the beta-adrenergic receptor (beta-AR) as well as the light-bleached form of rhodopsin. beta-ARK is present in a wide variety of mammalian tissues.
J L, Benovic +4 more
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Breast Cancer Research, 2022 Background Opioid and beta-adrenergic receptors are recently shown to cross talk via formation of receptor heterodimers to control the growth and proliferation of breast cancer cells.
Bénédicte Rousseau +3 more
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Beta-adrenergic receptor kinase: primary structure delineates a multigene family. [PDF]
, 1989 The beta-adrenergic receptor kinase (beta-ARK), which specifically phosphorylates only the agonist-occupied form of the beta-adrenergic and closely related receptors, appears to be important in mediating rapid agonist-specific (homologous ...
Benovic JL +4 more
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