Results 1 to 10 of about 295,622 (354)

Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma.

PLoS ONE, 2013
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable efficacy in the treatment of benign vascular tumors such as infantile hemangiomas.
Jessica M Stiles, Clarissa Amaya, Steven Rains, Dolores Diaz, Robert Pham, James Battiste, Jaime F Modiano, Victor Kokta, Laura E Boucheron, Dianne C Mitchell, Brad A Bryan   +10 more
doaj   +2 more sources

Clinical and morphological characteristics of head-facial haemangiomas [PDF]

Head & Face Medicine, 2007
Background Haemangiomas of the head or face are a frequent vascular pathology, consisting in an embryonic dysplasia that involves the cranial-facial vascular network.
Chiummariello Stefano, Torroni Andrea, Iannetti Giorgio, Cavallotti Carlo   +3 more
doaj   +3 more sources

Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling [PDF]

Pharmacogenomics and Personalized Medicine, 2014
Grazia Daniela Femminella,1 Vincenzo Barrese,2,3 Nicola Ferrara,1,4 Giuseppe Rengo4 1Department of Translational Medical Sciences, Federico II University, Naples, Italy; 2Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II
Femminella GD, Barrese V, Ferrara N, Rengo G   +3 more
doaj   +3 more sources

Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors [PDF]

iScience
Summary: G protein-coupled receptors (GPCRs) are major drug targets and key regulators of cell signaling. The basis of functional diversification between individual GPCRs and families of GPCRs can be revealed by investigating evolutionary conservation ...
Abigail Rose Walker, Berkay Selçuk, Ismail Erol, Serdar Durdağı, Aylin Carla Hanyaloglu, Ogün Adebali   +5 more
doaj   +2 more sources

Dissecting Beta-Adrenergic Receptors

JACC: Basic to Translational Science, 2023
J. David Port, PhD
doaj   +2 more sources

Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting [PDF]

, 2013
Aims: To compare the constitutive and agonist-dependent endosomal trafficking of α1A- and α1B-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype.
A Hirasawa, AC Hanyaloglu, AL Lattion, B Lei, BL Wolfe, C Moyano, C Stenbergen, CD Wright, D Calebiro, D Chalothorn, D Diviani, D Gesty-Palmer, D Wu, DM Perez, DP Morris, DP Morris, E Oliver, EJ Adie, EJ Adie, Elena Carceller, F Liu, Fermí Montó, Graeme Milligan, Ian Christie McGrath, James Porter, JB Morris, JD Pediani, JD Pediani, JL Benovic, John Pediani, KA DeFea, L Stanasila, LM Luttrell, M von Zastrow, María Antonia Noguera, MC Lyssand JS De Fino, Miguel Pérez-Aso, MW Lee, MY Tsang, P Lajoie, PA Patel, Pilar D’Ocon, RH Oakley, RR Price, S Ahn, S Alexander, S Keffel, S Mhaouty-Kodja, S Terrillon, SK Shenoy, SM DeWire, SS Ferguson, TL Theroux, Vanessa Segura, Y Huang   +54 more
core   +10 more sources

Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]

PLoS ONE, 2010
RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon, Robert Root-Bernstein, N Edward Robinson, William M Abraham, Catherine Berney   +4 more
doaj   +1 more source

Alpha and beta adrenergic receptors modulate keratinocyte migration.

PLoS ONE, 2021
Keratinocyte migration into skin wounds is the step of the healing process that correlates with the wound closure rate. Keratinocyte migration, and wound epithelialization are decreased when beta 2-adrenergic receptors (B2AR) are activated by 1 μM ...
Hsin-Ya Yang, Pieter Steenhuis, Aaron M Glucksman, Zhanna Gurenko, Thi Dinh La, R Rivkah Isseroff   +5 more
doaj   +1 more source

Beta Adrenergic Receptors in Keratinocytes [PDF]

Dermatologic Clinics, 2007
Beta2 adrenergic receptors were identified in keratinocytes more than 30 years ago, but their function in the epidermis continues to be elucidated. Abnormalities in their expression, signaling pathway, or in the generation of endogenous catecholamine agonists by keratinocytes have been implicated in the pathogenesis of cutaneous diseases such as atopic
Raja K, Sivamani, Susanne T, Lam, R Rivkah, Isseroff   +2 more
openaire   +2 more sources

THE PRINCIPLES OF USING ESMOLOL IN THE PRACTICE OF AN ANESTHESIOLOGIST AND AN INTENSIVE CARE PHYSICIAN

Клінічна та профілактична медицина, 2021
Aim of the study: to analyze the problem of using the beta-1-blocker esmolol for anesthetic management and intensive care from the sources of the modern available literature. Materials and methods. Bibliosemantic, comparative and systems analysis. The
V. I. Cherniy, T. V. Chernii, N.V. Shestak   +2 more
doaj   +1 more source