Results 41 to 50 of about 1,323,755 (303)

Pathways Involving Beta-3 Adrenergic Receptors Modulate Cold Stress-Induced Detrusor Overactivity in Conscious Rats [PDF]

, 2014
ObjectiveTo investigate pathways involving beta-3 adrenergic receptors (ARs) in detrusor overactivity induced by cold stress, we determined if the beta-3 AR agonist CL316243 could modulate the cold stress-induced detrusor overactivity in normal rats ...
Yamagishi, Takahiro, Minagawa, Tomonori, Nakazawa, Masaki, Ishizuka, Osamu, Yokoyama, Hitoshi, Imamura, Tetsuya, Ogawa, Teruyuki, Nishizawa, Osamu   +7 more
core   +1 more source

Adrenergic regulation of adipocyte metabolism.

Journal of Lipid Research, 1983
Adipocytes can be readily isolated from intact adipose tissue. In adipocytes from hamster and human white adipose tissue it is possible to demonstrate beta, alpha 1, and alpha 2 adrenoceptors.
J N Fain, J A Garcĩa-Sáinz
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Influence of development and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic responses

Journal of Lipid Research, 1983
The response of the hamster adipocyte to various lipolytic (beta-adrenergic) and antilipolytic (alpha(2)-adrenergic and adenosine-dependent) stimuli was studied during the development and after cold-induced regression of fat stores.
C Carpene, M Berlan, M Lafontan
doaj   +1 more source

BETA-ADRENERGIC RECEPTORS IN VARIOUS ORGANS

Japanese Journal of Pharmacology, 1970
The concept of two adrenergic receptor mechanisms or α- and β-adrenergic receptor systems, originally postulated by Ahlguist (1) is presently accepted. Furchgott (2) has presented evidence suggesting that there may be different types of receptors in the β- class.
TAKAGI, KEIJIRO, TAKAYANAGI, ISSEI
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Effect of a Reduced-Calorie Diet on alpha-2 Adrenergic Receptor Responsiveness in Abdominal Adipose Tissue in Obese Men During Exercise [PDF]

, 2008
There is at present an imperfect understanding of the effect of diet on availability of inhibitory receptors in fat cells during exercise among obese men. *Objective:* The purpose of this study was to determine whether diet results in
Roy R. Estrada, Joseph O. Schmelz, David Turbow, Edith Neumann   +3 more
core  

Circannual variation in the expression of beta 2-adrenoceptors on human peripheral mononuclear leukocytes (MNLs) [PDF]

, 1988
Peripheral mononuclear leukocytes (MNLs) are widely used as a tissue model in studies of beta-adrenoceptor disturbances in hypertension and asthmatic diseases.
Remien, J., I. Langenmayer, Haen, Ekkehard, Liebl, B., J. Remien, Haen, E., Pangerl, A., Langenmayer, Irmgard, B. Liebl, E. Haen, Langenmayer, I., A. Pangerl   +11 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Beta-adrenergic blocking agents in cutaneous and oral melanoma

Oral Oncology Reports
Beta-adrenergic blocking agents, or beta-blockers, are primarily used to manage cardiovascular conditions such as hypertension, heart failure, and arrhythmias by blocking the effects of stress hormones on beta-adrenergic receptors, reducing heart rate ...
Sivakamavalli Jeyachandran
doaj   +1 more source