Results 21 to 30 of about 1,323,755 (303)

Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma.

PLoS ONE, 2013
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable efficacy in the treatment of benign vascular tumors such as infantile hemangiomas.
Jessica M Stiles, Clarissa Amaya, Steven Rains, Dolores Diaz, Robert Pham, James Battiste, Jaime F Modiano, Victor Kokta, Laura E Boucheron, Dianne C Mitchell, Brad A Bryan   +10 more
doaj   +1 more source

An assay for beta-adrenergic receptors in isolated human fat cells.

Journal of Lipid Research, 1982
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt, P Arner, H Wahrenberg, J Ostman   +3 more
doaj   +1 more source

Preponderance of alpha 2- over beta 1-adrenergic receptor sites in human fat cells is not predictive of the lipolytic effect of physiological catecholamines

Journal of Lipid Research, 1983
Adrenergic control of human fat cell lipolysis is mediated by two kinds of receptor sites that are simultaneously stimulated by physiological amines. To establish a correlation between the binding characteristics of the receptor and biological functions,
M Lafontan, M Berlan, A Villeneuve
doaj   +1 more source

Beta-adrenergic receptors on MNL. [PDF]

Circulation, 1989
[No abstract available]
openaire   +2 more sources

Glycyrrhizic Acid Reduces Heart Rate and Blood Pressure by a Dual Mechanism

Molecules, 2016
Beta adrenergic receptors are crucial for their role in rhythmic contraction of heart along with their role in the pathological conditions such as tachycardia and high risk of heart failure.
Kailash Singh, Aung Moe Zaw, Revathi Sekar, Ahuja Palak, Ahmed A. Allam, Jamaan Ajarem, Billy K. C. Chow   +6 more
doaj   +1 more source

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease

Neurobiology of Disease, 2020
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of ...
Andrew K. Evans, Pooneh M. Ardestani, Bitna Yi, Heui Hye Park, Rachel K. Lam, Mehrdad Shamloo   +5 more
doaj   +1 more source

The Role of Beta-Adrenergic Receptors in Depression and Resilience

Biomedicines, 2022
Norepinephrine is a catecholamine neurotransmitter that has been extensively implicated in the neurobiology of major depressive disorder (MDD). An accumulating body of evidence indicates that investigations into the action of norepinephrine at the ...
Hongxing Zhang, Mengqiao Cui, Jun-Li Cao, Ming-Hu Han   +3 more
doaj   +1 more source

In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles

Cells, 2021
When myocardial function is compromised as in heart failure (HF), there is activation of the sympathetic nervous system with elevated circulating catecholamine levels.
Jin-Sook Kwon, Eric W. Barr, J. Kurt Chuprun, Walter J. Koch   +3 more
doaj   +1 more source

Genetic Polymorphism of beta1-adrenergic Receptors and the Effect on the Clinical Efficacy of beta-adrenoblockers

Рациональная фармакотерапия в кардиологии, 2021
Beta-adrenergic blockers are a valuable class of cardiovascular drugs and are widely used in the treatment of arterial hypertension (AH), coronary heart disease, chronic heart failure (CHF), cardiac arrhythmias, significantly improving the prognosis of ...
V. N. Larina, M. V. Leonova
doaj   +1 more source

Inhibition of the lipolytic action of beta-adrenergic agonists in human adipocytes by alpha-adrenergic agonists.

Journal of Lipid Research, 1981
The aim of this study was to define the role of the alpha-adrenergic receptor in the regulation of lipolysis by human adipocytes. Glycerol production by isolated human adipocytes was stimulated by the pure beta-adrenergic agonist isoproterenol in a dose ...
E E Wright, E R Simpson
doaj   +1 more source