Results 61 to 70 of about 104,267 (299)

PERIOPERATIVE BETA BLOCKER IN HIGH RISK PATIENTS UNDERGOING MAJOR ABDOMINAL SURGERY AND ITS EFFECT ON CARDIOVASCULAR MORTALITY AND MORBIDITY [PDF]

Ain Shams Medical Journal, 2019
Background: Perioperative cardiac complications are an important concern for the millions of individuals who undergo surgery worldwide every year. After surgery, 2% of these patients suffer major cardiac complications.
Lydia Zakhary, Rasha Hassan, Hoda Abdelsamie, Adel Alansary, Gehan Kamel   +4 more
doaj   +1 more source

The use of beta-blockers before major trauma and posttrauma outcome: A nationwide population-based study

Journal of Medical Sciences, 2022
Background: Beta-blockers are widely used for the treatment of arrhythmia, hypertension, and congestive heart failure. Major trauma causes significant blood loss and subsequent tachycardia and hypotension.
Jen-Chun Wang, Wu-Chien Chien, Chi-Hsiang Chung, Po-Chuan Chen, Chin-Li Chen, Shih-Hung Tsai   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Effectiveness of preJhospital betaJblocker therapy in patients with acute coronary syndrome

Российский кардиологический журнал, 2008
To assess the effectiveness of pre-hospital beta-blocker therapy in patients with acute coronary syndrome (ACS), 76 individuals with Q-wave myocardial infarction (Q-MI), and 62 persons with non-Q wave MI (non-Q-MI) were examined.
G. M. Baitova, Y. M. Madyarova, M. T. Beyshenkulov   +2 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

The effect of beta blockers on heart rate response during the Chester Step Test [PDF]

, 2011
The objective of this study is to ascertain that as the intensity of exercise increases through the stages of the Chester Step Test (CST) does the difference between the beta blocked(BB) and the non beta blocked(NBB) participants heart rate(HR) response ...
Gilchrest, Joanne
core  

Comparative study between oral and intralesional injection of beta-blocker in the treatment of infantile capillary hemangioma

Egyptian Pediatric Association Gazette
Purpose The present is conducted with the aim of comparing the clinical efficacy and side effects of oral versus intralesional propranolol treatment of infantile capillary hemangiomas.
Sahar S Sheta, Kareem B. Elessawy, Nadeen Eltoukhy, Ayman Esmail, Walaa ElNaggar   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source