Results 91 to 100 of about 710,673 (294)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
BMJ OpenObjectives To investigate the incidence and determinants of glaucoma in an elderly Chinese population, and clinical, mental health and economic impacts.Design This nationally representative, longitudinal study assessed self-reported 6-year (from 2011 to ...
Li Li +8 more
doaj +1 more source
Renormalised four-point coupling constant in the three-dimensional O(N) model with N=0
, 2007 We simulate self-avoiding walks on a cubic lattice and determine the second virial coefficient for walks of different lengths. This allows us to determine the critical value of the renormalized four-point coupling constant in the three-dimensional N ...
Andrea Pelissetto +15 more
core +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Risk, profitability and value of the leading steel producers on the world capital markets
Metalurgija, 2015 The purpose of the article is an assessment of risk, profitability and value as well as the relationships between these parameters for fifteen leading steel producers in the world.
I. Jonek-Kowalska
doaj
, 2013 The Lyman-$\beta$ forest refers to a region in the spectra of distant quasars that lies between the rest-frame Lyman-$\beta$ and Lyman-$\gamma$ emissions.
Bailey, Stephen +15 more
core +2 more sources
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Kinematic sensitivity to the Fierz term of $\beta$-decay differential spectra
, 2016 The current most stringent constraints on exotic scalar or tensor couplings in neutron and nuclear $\beta$ decay, involving left-handed neutrinos, are obtained from the Fierz interference term. The sensitivity to this term in a correlation coefficient is
Gonzalez-Alonso, Martin +1 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source